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Journal Articles

MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis

Jun Chul Kim, Young Y. Ou, Jose L. Badano, Muneer A. Esmail, Carmen C. Leitch, Elsa Fiedrich, Philip L. Beales, John M. Archibald, Nicholas Katsanis, Jerome B. Rattner, Michel R. Leroux
Journal: Journal of Cell Science
J Cell Sci (2005) 118 (5): 1007–1020.
https://doi.org/10.1242/jcs.01676
Published: 1 March 2005
... polypeptides. Here we show that MKKS/BBS6, one of several proteins associated with Bardet-Biedl syndrome (BBS), is a Group II chaperonin-like protein that has evolved recently in animals from a subunit of the eukaryotic chaperonin CCT/TRiC, and diverged rapidly to acquire distinct functions. Unlike other...
View article titled, MKKS&#x2F;<span class="search-highlight">BBS6</span>, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis
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Includes: Supplementary data