... of nuclear bodies known as interphase prenucleolar bodies (iPNBs) are formed in the nucleoplasm after hypotonic stress from partially disassembled nucleoli. iPNBs are then disassembled, and the nucleoli are reformed simultaneously. Here, we show that diffusion of B23 molecules (also known as nucleophosmin...

... with sizes similar to those present in the nucleoplasm. The TRF2 dots did not overlap with dots stemming from the upstream binding factor (UBF) or the B23 protein. After treatment with a low concentration of actinomycin D (0.05 μg/ml), TRF2 remained in the nucleolus, although this condition selectively...

... Astrocytes Shuttling HIV Rev PKI Importin β Exportin 1 B23 Ran/TC4 In eukaryotic cells, complex mechanisms have evolved for controlled transport of RNAs and proteins between cytoplasmic and nuclear compartments (for reviews, see Gorlich and Kutay, 1999 ; Izaurralde and Adam, 1998 ; Mattaj...

... hours post treatment was characterized by degradation of other nucleolar and nuclear proteins such as nuclear lamins, topoisomerase I and B23. In conclusion, remarkable segregation of nucleolar argyrophilic proteins, nucleolar RNA and a simultaneous activation of the cascade of caspases markedly...

...Olga V. Zatsepina; Annie Rousselet; Pui K. Chan; Mark O. J. Olson; E. G. Jordan; Michel Bornens ABSTRACT B23 is a major phosphoprotein in the interphasic nucleolus where it is involved in the assembly of pre-ribosomes. Using several cultured animal cells, we report that, in addition to the known...