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Keywords: Axonal transport
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Journal Articles
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2023) 136 (12): jcs260490.
Published: 26 June 2023
... progressive motor and sensory dysfunctions with significant sciatic nerve myelination deficits and neuromuscular degeneration. Additionally, increased microtubule stability, shown by a significant increase in tubulin acetylation and decrease in tubulin tyrosination, and decreased axonal transport were...
Includes: Supplementary data
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In collection:
Cytoskeleton
J Cell Sci (2023) 136 (12): jcs261223.
Published: 21 June 2023
...Amruta Vasudevan; Reshma Maiya; Keertana Venkatesh; Vinod Kumar; Parul Sood; Kausalya Murthy; Sandhya P. Koushika; Gautam I. Menon ABSTRACT Stationary clusters of vesicles are a prominent feature of axonal transport, but little is known about their physiological and functional relevance to axonal...
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Motors
J Cell Sci (2023) 136 (5): jcs260220.
Published: 31 October 2022
... transport ( Sleigh et al., 2019 ). Dync1h1 encodes the heavy chain of the cytoplasmic dynein 1 motor protein, which plays a key role in retrograde axonal transport in neurons. Various mutations in human DYNC1H1 have been associated with neurological diseases, including spinal muscular atrophy, Charcot...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2020) 133 (3): jcs241802.
Published: 13 February 2020
...-translational modifications of tubulin are emerging as mechanisms for regulating microtubule functions, but their impact on neuronal transport is only marginally understood. Here, we have systematically studied the impact of post-translational polyglutamylation on axonal transport. In cultured hippocampal...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (3): jcs241802.
Published: 13 February 2020
...-translational modifications of tubulin are emerging as mechanisms for regulating microtubule functions, but their impact on neuronal transport is only marginally understood. Here, we have systematically studied the impact of post-translational polyglutamylation on axonal transport. In cultured hippocampal...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (23): jcs234492.
Published: 2 December 2019
....2016.12.020 Bilsland , L. G. , Sahai , E. , Kelly , G. , Golding , M. , Greensmith , L. and Schiavo , G. ( 2010 ). Deficits in axonal transport precede ALS symptoms in vivo . Proc. Natl. Acad. Sci. USA   107 , 20523 - 20528 . 10.1073/pnas.1006869107 Burke , R. E...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (23): jcs234492.
Published: 2 December 2019
... (NMJ) and contribute to the production of most of the NMJ ATP, unlike what is found in sympathetic neurons. Axonal transport Mitochondria Neuromuscular junction Motor neuron Sympathetic neuron Synaptic ATP Israel Science foundation 10.13039/501100003977 735/19 European...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2019) 132 (2): jcs219774.
Published: 16 January 2019
...://www.biologists.com/user-licence-1-1/ Summary: LGI1 is enriched at the axon initial segment of hippocampal neurons with ADAM22 and Kv1 channel proteins, and LGI1 mutations associated with epilepsy prevent its recruitment at that site. Hippocampal neurons Axonal transport Epilepsy ADLTE K...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (2): jcs219774.
Published: 16 January 2019
...://www.biologists.com/user-licence-1-1/ Summary: LGI1 is enriched at the axon initial segment of hippocampal neurons with ADAM22 and Kv1 channel proteins, and LGI1 mutations associated with epilepsy prevent its recruitment at that site. Hippocampal neurons Axonal transport Epilepsy ADLTE K...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2017) 130 (19): 3388–3398.
Published: 1 October 2017
... motor neurons requires the cut up gene revealing a role in cargo specificity for the LC8 family of dynein light chains. Axonal transport Proteasome LC8 dynein light chain Drosophila Proteasomes are large protein complexes responsible for degradation of normal short-lived...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (19): 3388–3398.
Published: 1 October 2017
... motor neurons requires the cut up gene revealing a role in cargo specificity for the LC8 family of dynein light chains. Axonal transport Proteasome LC8 dynein light chain Drosophila Ellison Medical Foundation 10.13039/100000863 AG-NS-0415-07 National Institutes...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (15): 2520–2529.
Published: 1 August 2017
... and older distal DCVs. Traffic studies show that DCV axonal transport and synaptic capture are not scaled for extensive innervation, thus limiting distal delivery. Activity-induced synaptic endocytosis and synaptic neuropeptide release are also reduced distally. We propose that limits in organelle transport...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (15): 2520–2529.
Published: 1 August 2017
... and older distal DCVs. Traffic studies show that DCV axonal transport and synaptic capture are not scaled for extensive innervation, thus limiting distal delivery. Activity-induced synaptic endocytosis and synaptic neuropeptide release are also reduced distally. We propose that limits in organelle transport...
Includes: Supplementary data