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Keywords: Axon regeneration
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Cytoskeleton
J Cell Sci (2023) 136 (12): jcs260490.
Published: 26 June 2023
... observed in Scg10 knockout dorsal root ganglion (DRG) neurons. Furthermore, SCG10 depletion impaired axon regeneration in both injured mouse sciatic nerve and cultured DRG neurons following replating, and the impaired axon regeneration was found to be induced by a lack of SCG10-mediated microtubule...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (7): jcs251967.
Published: 15 April 2021
... and this localization selectively increases in vivo during peripheral nervous system (PNS) axon regeneration. Functional studies indicate that prenyl-Cdc42 increases axon length in a manner that requires axonal targeting of its mRNA, which, in turn, needs an intact C-terminal CaaX motif that can drive prenylation...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2006) 119 (13): 2787–2796.
Published: 1 July 2006
... in regenerating neurons is probably due to the ability of regenerating neurons to assemble axons using an integrin-independent pathway. Finally, our data show that the GSK-3β-APC pathway, previously shown to mediate developing axon growth, is also necessary for axon regeneration. Failure of axon regeneration...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (5): 863–872.
Published: 1 March 2005
.... As astrocytes matured after postnatal day 4, axonal regeneration was inhibited in mice overexpressing Bcl-2. Concurrent induction of Bcl-2 and attenuation of reactive gliosis reversed the failure of CNS axonal re-elongation in postnatal mice and led to rapid axonal regeneration over long distances...
Journal Articles
Journal Articles
J Cell Sci (1994) 107 (6): 1687–1695.
Published: 1 June 1994
... that do not lies in the level of production of a dermatan/keratan sulphate proteoglycan. * Author for correspondence at address 1 14 12 1993 25 02 1994 © 1994 by Company of Biologists 1994 astrocyte extracellular matrix proteoglycan laminin axon regeneration...
Journal Articles
J Cell Sci (1992) 103 (2): 571–579.
Published: 1 October 1992
.... The presence of astrocytes therefore alters the results of axonal contact with oligodendrocytes. * Author for correspondence 27 05 1992 23 07 1992 © 1992 by Company of Biologists 1992 axon growth axon regeneration astrocyte oligodendrocyte growth cone Axons fail...
Journal Articles
J Cell Sci (1989) 92 (1): 93–100.
Published: 1 January 1989
...J. W. Fawcett; J. Rokos; I. Bakst ABSTRACT We have examined the interactions between axons regenerating from dorsal root ganglia (DRGs) derived from newborn rats and oligodendrocytes cultured by three different techniques. Cultures examined after 2 days have a profuse outgrowth of axons from...