... medium provided that the original work is properly attributed. Highlighted Article: Tau and MAP6 play antagonistic roles in regulating multiple aspects of neuronal development, presumably via their antagonistic effects on microtubule dynamics. Tau MAP6 Microtubule Axon growth Growth...

...Rosa E. Mino; Stephen L. Rogers; April L. Risinger; Cristina Rohena; Swati Banerjee; Manzoor A. Bhat ABSTRACT Axonal growth and targeting are fundamental to the organization of the nervous system, and require active engagement of the cytoskeleton. Polymerization and stabilization of axonal...

... not distinguish functions of the locally generated NMP35 protein. Using axonally targeted versus cell-body-restricted NMP35 constructs, we show that NMP35 supports axonal growth, and overexpression of an axonally targeted NMP35 mRNA is sufficient to increase axonal outgrowth. * Author for correspondence...

... in brain development. * Author for correspondence ( [email protected] ) 6 8 2012 © 2012. Published by The Company of Biologists Ltd 2012 Gprin Axon growth Proteomics GAP-43 Cytoskeleton Nicotine Neurite Bungarotoxin Growth cone Neuronal development is marked...

.... By reducing β-catenin availability using shRNA-mediated gene silencing or expression of intracellular N-cadherin, we show that β-catenin is required for axon growth downstream of brain-derived neurotrophic factor (BDNF) signalling and hepatocyte growth factor (HGF) signalling. We demonstrate that the receptor...

... in embryonic dorsal root ganglia from wild-type mice. Vitronectin addition to cultured dorsal root ganglia induced axonal growth, which could be mimicked by vitronectin peptide 307-320 and abrogated by anti-PrP C antibodies. Full-length vitronectin, but not the vitronectin peptide 307-320, induced axonal...

...James W. Fawcett; N. Fersht; L. Housden; M. Schachner; P. Pesheva ABSTRACT Axon growth in vitro may be inhibited by contact with oligodendrocytes, but most axons grow readily on the surface of astrocyte monolayers. Since both cell types are in close contact with one another in the damaged nervous...