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Keywords: Aurora A kinase
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Journal Articles
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J Cell Sci (2020) 133 (12): jcs243071.
Published: 16 June 2020
... required for assembly of the interphase mitochondrial network after mitosis. This article has an associated First Person interview with the first authors of the paper. Aurora A kinase Cdh1 FZR1 TPX2 Mitochondria Mitosis Widespread reports in the literature of interphase activity of AURKA...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (15): 3015–3025.
Published: 1 August 2016
... the cortical forces that act on astral microtubules to properly position the spindle are modulated is incompletely understood. Here, we report that the PP6 phosphatase PPH-6 and its associated subunit SAPS-1, which positively regulate pulling forces acting on spindle poles, associate with the Aurora A kinase...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (19): 3543–3549.
Published: 1 October 2015
... transition. PDGFR-mediated PLCγ signaling induces deciliation by activating intracellular Ca 2+ release and, thereby, AURKA. Aurora A kinase PLCγ Platelet-derived growth factor receptor Deciliation Gastrointestinal stromal tumor Primary cilia Primary cilia comprise a microtubule axoneme...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (5): 1204–1216.
Published: 1 March 2012
... retrovirus. ( C ) Inhibition of Aurora A kinase using 1-NM-PP1 activity reduces LIMK2 levels. AA-MDA and AA-as7-MDA cells were treated with either DMSO or 250 nM 1-NM-PP1 for 12 hours, and Aurora A and LIMK2 levels analyzed. ( D ) Aurora A inhibits LIMK2 degradation. MDA and AA-MDA cells were treated...