1-15 of 15
Keywords: Astrocytes
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2021) 134 (16): jcs258419.
Published: 20 August 2021
... investigated (i) the signaling competence of mouse embryonic and postnatal primary cortical astrocytes exposed to brain-derived neurotrophic factor (BDNF) and, (ii) the role of kinase D-interacting substrate of 220 kDa (Kidins220), a transmembrane scaffold protein that mediates neurotrophin signaling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (12): jcs258430.
Published: 17 June 2021
... analysis. It extracts 23 morphometric features based on cell images and Sholl analysis parameters, followed by principal component analysis (PCA). SMorph was tested on neurons, astrocytes and microglia and reveals subtle changes in cell morphology. Using SMorph, we found that chronic 21-day treatment...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (7): jcs239756.
Published: 08 April 2020
...Marc Oudart; Romain Tortuyaux; Philippe Mailly; Noémie Mazaré; Anne-Cécile Boulay; Martine Cohen-Salmon ABSTRACT Astrocytes are morphologically complex and use local translation to regulate distal functions. To study the distribution of mRNA in astrocytes, we combined mRNA detection via in situ...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (21): 3878–3887.
Published: 01 November 2015
... metabolite galactosylsphingosine (psychosine) in the brain. Here we find that psychosine induces human astrocyte cell death probably via an apoptotic process in a concentration- and time-dependent manner (EC50∼15 μM at 4 h). We show these effects of psychosine are attenuated by pre-treatment...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (20): 4368–4380.
Published: 15 October 2014
...) is the main intermediate filament in astrocytes and is regulated by epigenetic mechanisms during development. We demonstrate that histone acetylation also controls GFAP expression in mature astrocytes. Inhibition of histone deacetylases (HDACs) with trichostatin A or sodium butyrate reduced GFAP expression...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (7): 1081–1088.
Published: 01 April 2010
... affects the function of various tumor-cell types. Here, we demonstrate that CXCR7 is an active component of SDF-1 signalling in astrocytes and Schwann cells. Cultured cortical astrocytes and peripheral nerve Schwann cells exhibit comparable total and cell-surface levels of expression of both SDF-1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (3): 351–359.
Published: 01 February 2010
..., there is no difference in the amino acid sequence of the protein. The N-terminus of GS, which constitutes a ‘weak’ mitochondrial targeting signal (MTS), is sufficient to direct a chimeric protein to the mitochondria in hepatocytes and to the cytoplasm in astrocytes. Considering that a weak MTS is dependent on a highly...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (19): 3462–3471.
Published: 01 October 2009
... in neuronal Thy-1 triggers formation of focal adhesions and stress fibers in astrocytes via RhoA activation. A putative heparin-binding domain is present in Thy-1, raising the possibility that this membrane protein stimulates astrocyte adhesion via engagement of an integrin and the proteoglycan syndecan-4...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (7): 1267–1277.
Published: 01 April 2007
...Runfeng Jing; Ulrika Wilhelmsson; William Goodwill; Lizhen Li; Yihang Pan; Milos Pekny; Omar Skalli Immature astrocytes and astrocytoma cells contain synemin and three other intermediate filament (IF) proteins: glial fibrillary acidic protein (GFAP), vimentin and nestin. Here, we show that, after...
Journal Articles
J Cell Sci (2006) 119 (21): 4452–4461.
Published: 01 November 2006
...-regulated by ischemia in astrocytes and may play a specific protective role in astrocytes. Here we report that 14-3-3γ associates with both soluble and filamentous GFAP in a phosphorylation- and cell-cycle-dependent manner in primary cultured astrocytes. The amount of association increases during G2/M phase...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (2): 271–282.
Published: 15 January 2006
... that astrocytes exposed to ethanol undergo morphological changes associated with anoikis, including the peripheral reorganization of both focal adhesions and actin-myosin system, cell contraction, membrane blebbing and chromatin condensation. We found that either the small GTPase RhoA or its effector ROCK-I (Rho...
Journal Articles
J Cell Sci (2004) 117 (18): 4067–4076.
Published: 15 August 2004
.... In a previous work we demonstrated that laminin molecules could self-assemble in two different manners, giving rise to matrices that could favor either neuritogenesis or proliferation of cortical precursor cells. We investigated whether the ability of astrocytes to promote neuritogenesis of co-cultivated...
Journal Articles
J Cell Sci (2003) 116 (14): 2845–2855.
Published: 15 July 2003
..., and suggest that they may be part of the focal adhesion kinase regulatory complex. * Author for correspondence (e-mail: oliver@bogler.net ) 31 3 2003 © The Company of Biologists Limited 2003 2003 Glioma Astrocytes SETA/CIN85/Ruk AIP1 Focal adhesion kinase Cytoskeleton Electrical...
Journal Articles
J Cell Sci (2002) 115 (16): 3331–3340.
Published: 15 August 2002
...Carla Perego; Cristina Vanoni; Silvia Massari; Andrea Raimondi; Sandra Pola; Maria Grazia Cattaneo; Maura Francolini; Lucia Maria Vicentini; Grazia Pietrini As little is known about the role of cadherin-mediated cell-cell adhesion in astrocytes and its alteration in migrating and invasive...
Journal Articles
J Cell Sci (1988) 1988 (Supplement_10): 77–83.
Published: 01 February 1988
...MARTIN C. RAFF; LAURA E. LILLIEN Summary In the rat central nervous system (CNS) oligodendrocytes and type-2 astrocytes are thought to develop from a common precursor – the O-2A progenitor cell. Oligodendrocytes develop first and make myelin; type-2 astrocytes develop later and extend processes...