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1-20 of 22
Keywords: Astrocyte
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Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (2): jcs251629.
Published: 22 January 2021
... studied in neurons, whose cytoplasmic protrusions may be more than 1000 times longer than the diameter of the cell body. Importantly, alterations in local translation in neurons have been implicated in several neurological diseases. Astrocytes, the most abundant glial cells in the brain, are voluminous...
Journal Articles
In collection:
Lipid biology
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (1): 21–26.
Published: 1 January 2014
...; however, antioxidant therapies targeting brain diseases have been unsuccessful. Such failure might be related to inhibition of ROS-induced signalling in the brain. Using direct kinetic measures of lipid peroxidation in astrocytes and measurements of lipid peroxidation products in brain tissue, we here...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2013) 126 (17): 3873–3883.
Published: 1 September 2013
...Kai Murk; Elena M. Blanco Suarez; Louisa M. R. Cockbill; Paul Banks; Jonathan G. Hanley Summary Astrocytes exhibit a complex, branched morphology, allowing them to functionally interact with numerous blood vessels, neighboring glial processes and neuronal elements, including synapses. They also...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2012) 125 (4): 844–857.
Published: 15 February 2012
... of the Cdc42-mediated polarity pathway and centrosome reorientation do not occur. Re-expression of N-cadherin in gliomas restores cell polarity and strongly reduces cell velocity, suggesting that loss of N-cadherin could contribute to the invasive capacity of tumour astrocytes. * Present address...
Includes: Multimedia, Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (11): 1959–1968.
Published: 1 June 2010
... and radial glia cells of the ventricular zone and immature neurons outside the ventricular zone but its expression disappears spontaneously as development proceeds except in GFAP-positive astrocytes. In cultured neurospheres, meteorin activates STAT3, and in turn increases the transcriptional activity...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2009) 122 (18): 3340–3350.
Published: 15 September 2009
...Sabine I. Mayer; Oliver G. Rössler; Takeshi Endo; Patrick Charnay; Gerald Thiel Stimulation of astrocytes with epidermal growth factor (EGF) induced proliferation and triggered the biosynthesis of the transcription factor Egr-1, involving the activation of the extracellular signal-regulated...
Includes: Supplementary data
Journal Articles
Samira Saadoun, Marios C. Papadopoulos, Hiroyuki Watanabe, Donghong Yan, Geoffrey T. Manley, A. S. Verkman
Journal:
Journal of Cell Science
J Cell Sci (2005) 118 (24): 5691–5698.
Published: 15 December 2005
... 9 2005 © The Company of Biologists Limited 2005 2005 AQP4 Astrocyte Chemotaxis Reactive gliosis Water channel The central nervous system (CNS) in mammals ( Pekny and Nilsson, 2005 ), amphibia ( Wujek and Reier, 1984 ), birds ( Lurie and Rubel, 1994 ), reptiles ( Romero...
Journal Articles
Nathalie Duval, Danielle Gomès, Viviane Calaora, Alessandra Calabrese, Paolo Meda, Roberto Bruzzone
Journal:
Journal of Cell Science
J Cell Sci (2002) 115 (16): 3241–3251.
Published: 15 August 2002
... into the three main cell types of the central nervous system (CNS), that is, astrocytes, neurons and oligodendrocytes. To study the possible role of connexins and junctional communication during differentiation of neural progenitors, we assessed cell-to-cell communication by microinjecting Lucifer Yellow...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (20): 3717–3725.
Published: 15 October 2001
.... Because growth factors are generally believed to regulate glial functions, we addressed their possible contribution to GLAST regulation in cultured rat astrocytes. Of the six growth factors tested (basic fibroblast growth factor (bFGF), insulin-like growth factor-1 (IGF-1), epidermal growth factor (EGF...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (5): 987–998.
Published: 1 March 2001
... processes of Bergmann glia in the molecular layer, and colocalized with astrocytes and granule cells in the granule cell layer. These results identify a direct association of Kir2.1, Kir2.2 and Kir2.3 with the MAGUK family member SAP97 that may form part of a macromolecular signaling complex in many...
Journal Articles
Richard Milner, Xiaozhu Huang, Jianfeng Wu, Stephen Nishimura, Robert Pytela, Dean Sheppard, Charles ffrench-Constant
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (23): 4271–4279.
Published: 1 December 1999
...Richard Milner; Xiaozhu Huang; Jianfeng Wu; Stephen Nishimura; Robert Pytela; Dean Sheppard; Charles ffrench-Constant ABSTRACT The Αv integrins are likely to be an important group of molecules for regulating astrocyte behaviour within the central nervous system. Together with their ligand...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1996) 109 (5): 1029–1039.
Published: 1 May 1996
...-crystallin in astrocytes in response to physiological stress of different types and asked what component of this induction is effected at the transcriptional level and whether activation of heat shock factor 1 and AP1 might account for these events. We have found that stress regulated induction of αB...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1995) 108 (11): 3523–3530.
Published: 1 November 1995
...Emma J. Williams; Bina Mittal; Frank S. Walsh; Patrick Doherty ABSTRACT We have cultured cerebellar neurons on monolayers of cortical astrocytes in control medium or medium containing recombinant basic fibroblast growth factor (FGF). FGF was found to inhibit neurite outgrowth, with a significant...
Journal Articles
Increased axon regeneration in astrocytes grown in the presence of proteoglycan synthesis inhibitors
Linda C. Smith-Thomas, James Stevens, Juin Fok-Seang, Andreas Faissner, John H. Rogers, James W. Fawcett
Journal:
Journal of Cell Science
J Cell Sci (1995) 108 (3): 1307–1315.
Published: 1 March 1995
...Linda C. Smith-Thomas; James Stevens; Juin Fok-Seang; Andreas Faissner; John H. Rogers; James W. Fawcett ABSTRACT We have recently reported that the critical difference between astrocytic cell lines that are good or poor promoters of axon growth lies in the extracellular matrix. We demonstrated...
Journal Articles
Manuel Portolés, Magdalena Faura, Jaime Renau-Piqueras, Francisco José Iborra, Rosana Saez, Consuelo Guerri, Joan Serratosa, Eulalia Rius, Oriol Bachs
Journal:
Journal of Cell Science
J Cell Sci (1994) 107 (12): 3601–3614.
Published: 1 December 1994
... and astrocyte precursor cells, and in proliferating and differentiated astrocytes in primary cultures by immunogold-labeling methods. In non-dividing cells nuclear calmodulin was mostly localized in heterochromatin although it was also present in euchro- matin and nucleoli. A similar pattern was observed...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1994) 107 (9): 2499–2508.
Published: 1 September 1994
...B. Jiang; G. I. Liou; M. A. Behzadian; R. B. Caldwell ABSTRACT Vasculogenesis is the formation of blood-vessels by differentiation of vascular precursor cells. Experiments using retinal models were designed to test the hypothesis that astrocytes influence this process by effects on the composition...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1994) 107 (7): 1783–1796.
Published: 1 July 1994
...M.-C. Tiveron; M. Nosten-Bertrand; H. Jani; D. Garnett; E. M. A. Hirst; F. Grosveld; R. J. Morris ABSTRACT The surface glycoprotein, Thy-1, when expressed by transfection in NG115/401L neural cells, inhibits their neurite outgrowth over astrocytes. We have investigated the role...
Journal Articles
Linda C. Smith-Thomas, Juin Fok-Seang, James Stevens, Jian-Sheng Du, Elizabeth Muir, Andreas Faissner, Herbert M. Geller, John H. Rogers, James W. Fawcett
Journal:
Journal of Cell Science
J Cell Sci (1994) 107 (6): 1687–1695.
Published: 1 June 1994
...Linda C. Smith-Thomas; Juin Fok-Seang; James Stevens; Jian-Sheng Du; Elizabeth Muir; Andreas Faissner; Herbert M. Geller; John H. Rogers; James W. Fawcett ABSTRACT We have produced a number of astrocytic cell lines, some of which promote abundant neurite outgrowth, some of which are poor promoters...
Journal Articles
Hartwig Wolburg, Jochen Neuhaus, Uwe Kniesel, Bodo Krauß, Eva-Maria Schmid, Mücella Öcalan, Catherine Farrell, Werner Risau
Journal:
Journal of Cell Science
J Cell Sci (1994) 107 (5): 1347–1357.
Published: 1 May 1994
.... On the other hand, the P-face asso- ciation of tight junction particles was enhanced by elevation of cAMP levels and by coculture of endothelial cells with astrocytes or exposure to astrocyte-conditioned medium. The latter effect on P-face association was induced by astrocytes but not fibroblasts. Elevation...
Journal Articles
Jean-Marc Verbavatz, Alfred N. Van Hoek, Tonghui Ma, Ivan Sabolic, Giovanna Valenti, Mark H. Ellisman, Dennis A. Ausiello, A. S. Verkman, Dennis Brown
Journal:
Journal of Cell Science
J Cell Sci (1994) 107 (4): 1083–1094.
Published: 1 April 1994
..., indicating that principal cell basolateral membranes contain a novel member of the CHIP/MIP family. Because this antibody also stained brain astrocyte end feet, which are enriched in OAPs, it is possible that the 28 kDa protein is related to these structures. We conclude that OAPs probably contain related...
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