...Riikka Pietilä; Marjut Nätynki; Tuomas Tammela; Jaakko Kangas; Kristina H. Pulkki; Nisha Limaye; Miikka Vikkula; Gou Young Koh; Pipsa Saharinen; Kari Alitalo; Lauri Eklund Angiopoietin 1 (Ang1) is an activating ligand for the endothelial receptor tyrosine kinase Tie2, whereas Ang2 acts as a context...

... suppressed formation of VEGF/FGF2-stimulated CLS. Angiopoietin 1 (Ang1) prevented regression of the TGFβ1-induced CLS, an effect that was blocked by angiopoietin 2 (Ang2), but required the continuous presence of VEGF. * Author for correspondence (e-mail: [email protected] ) 27...

...Marion Scharpfenecker; Ulrike Fiedler; Yvonne Reiss; Hellmut G. Augustin The angiopoietins Ang-1 and Ang-2 have been identified as ligands of the endothelial receptor tyrosine kinase Tie-2, which controls vascular assembly and endothelial quiescence. The largely complementary phenotypes of Ang-1...