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Keywords: Androgen receptor
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Journal Articles
J Cell Sci (2021) 134 (14): jcs258332.
Published: 28 July 2021
...Fatma Özgün; Zeynep Kaya; Tunç Morova; Bart Geverts; Tsion E. Abraham; Adriaan B. Houtsmuller; Martin E. van Royen; Nathan A. Lack ABSTRACT Androgen receptor (AR) splice variants are proposed to be a potential driver of lethal castration-resistant prostate cancer. AR splice variant 7 (ARv7...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (8): 1970–1979.
Published: 15 April 2012
...Martin E. van Royen; Wiggert A. van Cappellen; Carola de Vos; Adriaan B. Houtsmuller; Jan Trapman Androgen-regulated gene expression is a highly coordinated dynamic process mediated by androgen receptor (AR) ligand binding and DNA binding, and by specific AR protein–protein interactions. The latter...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (2): 266–276.
Published: 15 January 2010
...Laura E. Lamb; Beatrice S. Knudsen; Cindy K. Miranti The androgen receptor (AR) is expressed in differentiated secretory prostate epithelial cells in vivo. However, in the human prostate, it is unclear whether androgens directly promote the survival of secretory cells, or whether secretory cells...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (15): 2578–2587.
Published: 01 August 2008
...Hongbo Wang; Daqian Sun; Peng Ji; James Mohler; Liang Zhu Androgen–androgen-receptor (androgen-AR) signaling in normal prostate epithelium promotes terminal luminal epithelial cell differentiation. In androgen-dependent prostate-cancer cells, androgen-AR signaling gains the ability to promote both...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (7): 957–968.
Published: 01 April 2008
...Mark L. Cutress; Hayley C. Whitaker; Ian G. Mills; Murray Stewart; David E. Neal Ligand-dependent nuclear import is crucial for the function of the androgen receptor (AR) in both health and disease. The unliganded AR is retained in the cytoplasm but, on binding 5α-dihydrotestosterone...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (18): 4187–4198.
Published: 15 September 2005
...Pascal Farla; Remko Hersmus; Jan Trapman; Adriaan B. Houtsmuller The androgen receptor (AR) is essential for development of the male gender and in the growth of the majority of prostate cancers. Agonists as well as most antagonists induce translocation of the receptor to the nucleus, whereas only...