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Keywords: Amyloid-β peptide
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Journal Articles
Valérie Vingtdeux, Pallavi Chandakkar, Haitian Zhao, Lionel Blanc, Santiago Ruiz, Philippe Marambaud
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (13): 2330–2338.
Published: 1 July 2015
... in Alzheimer's disease. In the mouse brain, its levels are controlled by the CALHM1 ion channel promoting its clearance by insulin-degrading enzyme. CALHM1 Ion channel Amyloid-β peptide Insulin-degrading enzyme Secretion Alzheimer's disease Alzheimer's disease is a neurodegenerative brain...
Journal Articles
Ayae Kinoshita, Hiroaki Fukumoto, Tejal Shah, Christa M. Whelan, Michael C. Irizarry, Bradley T. Hyman
Journal:
Journal of Cell Science
J Cell Sci (2003) 116 (16): 3339–3346.
Published: 15 August 2003
...Ayae Kinoshita; Hiroaki Fukumoto; Tejal Shah; Christa M. Whelan; Michael C. Irizarry; Bradley T. Hyman Amyloid-β peptide, which accumulates in senile plaques in Alzheimer's disease, is derived from the amyloid precursor protein (APP) by proteolytic processing. β-secretase (Asp2), which cleaves APP...