1-7 of 7
Keywords: Ageing
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2018) 131 (14): jcs212977.
Published: 27 July 2018
... and differentiation of mouse skeletal muscle stem cells, and how their modulation can influence the cell state. We show that quiescent satellite stem cells have low energetic demands and perturbed oxidative phosphorylation during ageing, which is also the case for cells from post-mortem tissues. We show also...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (10): 1772–1784.
Published: 15 May 2017
... integrity of the synapse – mutant NMJs present with progressive structural changes and upregulated autophagy, features commonly observed during ageing and in models of neurodegeneration. Unexpectedly, we find instances of nerve terminal detachment from the muscle fibre; to our knowledge, this is the first...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (21): 4963–4971.
Published: 01 November 2012
... by PGC1α contribute to an increase in oxidative metabolism and the preservation of ROS homeostasis. Finally, we examine the importance of these findings in ageing and neurodegenerative disorders, conditions that are associated with impaired mitochondrial functions and ROS balance. Box 2. Respiration...
Journal Articles
J Cell Sci (2011) 124 (9): 1363–1372.
Published: 01 May 2011
... that are involved in a wide range of cellular processes during all stages of life, from development to ageing, and during homeostasis and stress. This Commentary discusses some lesser-known functional and regulatory aspects of IFs. We specifically address the emerging roles of nestin in myogenesis and cancer cell...
Journal Articles
J Cell Sci (2005) 118 (20): 4813–4821.
Published: 15 October 2005
.../unit length decreases in larger fibres during skeletal muscle ageing. This leads to an increased size of nuclear domain (quantity of cytoplasm/number of nuclei within that cytoplasm). Initially, larger fibres have more satellite cells than small fibres, but this advantage is lost as satellite cells...
Journal Articles
J Cell Sci (2004) 117 (11): 2417–2426.
Published: 01 May 2004
...David J. Kurz; Stephanie Decary; Ying Hong; Elisabeth Trivier; Alexander Akhmedov; Jorge D. Erusalimsky Replicative senescence and oxidative stress have been implicated in ageing, endothelial dysfunction and atherosclerosis. Replicative senescence is determined primarily by telomere integrity...
Journal Articles
J Cell Sci (2003) 116 (7): 1349–1357.
Published: 01 April 2003
... this has been thought to be causal in the accelerated ageing of this disease, controversy remains as to whether Werner syndrome is showing the acceleration of a normal cellular ageing mechanism or the occurrence of a novel Werner-syndrome-specific process. Here,we analyse the signalling pathways...