... to the nucleus ( Giannakakou et al., 2002 ). Adenovirus predominantly infects epithelial cells of the respiratory and gastrointestinal tracts, and conjunctiva ( Robinson et al., 2013 ). The species C human adenoviruses (HAdV-C2 and -C5) are widespread, persist in adenoid tissue and are life-threatening...

.... , Vogelstein B. ( 1998 ). A simplified system for generating recombinant adenoviruses . Proc. Natl. Acad. Sci. USA 95 , 2509 - 2514 . Hollmann K. H. ( 1974 ). Cytology and fine structure of the mammary gland . In Lactation , Vol. 1 (ed. Larson B. L. , Smith V. R. ), pp. 3...

... this is accomplished, which viral proteins are involved or indeed what benefits the virus derives from these effects is only just beginning to be understood. Adenoviruses contain a linear dsDNA genome of approximately 36 kb that is replicated in the nucleus of the host cell ( Liu et al., 2003 ; Shenk, 2001...

... interest in developing adenoviruses as defective vectors to carry and express foreign genes for research and therapeutic purposes ( Yeh and Perricaudet, 1997 ; Benihoud et al., 1999 ; Mountain, 2000 ). These vectors present several advantages: (1) their genomes are easily manipulated in vitro, (2) give...

...–1) and IFN-γ(10 ng ml–1)] during a period of 24 hours compared with controls (Ctrl). All lanes were loaded with 50 μg total proteins and normalized with tubulin (Tub). IB1/JIP-1 content was experimentally modulated in β cells using adenovirus gene transfer. We used recombinant adenoviruses...

... gene in 3T3L1 adipocytes on (pro)insulin release and glucose uptake. The human preproinsulin gene was transferred into 3T3L1 adipocytes by infecting the cells with recombinant adenovirus Adex1CA human preproinsulin. Immunocytochemical studies showed that (pro)insulin is associated with vesicular...

... is increased by two fold ( Fig. 5 ). These data indicate that the JNK activity is controlled, in non-stressed conditions, by the IB1/JIP-1 content. IB1/JIP-1 content was experimentally modulated in urothelium using a recombinant adenovirus gene transfer approach. We used recombinant adenoviruses...

... for providing the recombinant adenoviruses, CAG-CATZ mouse line and R26R mice, respectively and Shirley Small for animal husbandry. Jason Gay, Stacey Tepera and Bryan Welm provided invaluable assistance with the MEC transplantations and Maranke Koster in the analysis of the outgrowths. This research...

... Mexico † Author for correspondence 06 04 1993 02 06 1993 © 1993 by Company of Biologists 1993 adenovirus nucleolus translation RNA localization Adenovirus 2 (Ad2) belongs to subgroup C of adenoviruses, which have the ability to transform cells. The virion...