.... Inhibition of ROCK activity in ARHGAP32 -knockout (KO) cells effectively restored desmosomal organization and the integrity of epithelial cell sheets. Moreover, loss of DSP impaired desmosomal ARHGAP32 location and led to decreased actomyosin contractility. ARHGAP32 with a deletion of the GAB2-ID domain...

... for S100A11 in promoting actomyosin contractility-driven FA disassembly. * These authors contributed equally to this work ‡ Author for correspondence ( [email protected] ) Handling Editor: Michael Way Competing interests The authors declare no competing...

... contractility underlie this transition. Actomyosin contractility Apical constriction Cell migration Drosophila Pulsed contractions Biotechnology and Biological Sciences Research Council 10.13039/501100000268 BB/M021084/1 During development, morphogenetic processes ultimately...

... can fine-tune tissue morphology during development. Rho signaling Epithelial morphogenesis Actomyosin contractility Developmental mechanics Non-muscle Myosin-II Zipper Drosophila melanogaster National Institutes of Health 10.13039/100000002 GM117708 HD083185 GM007229...

...) by decreasing both actomyosin contractility and tugging forces at endothelial cell junctions. EMMPRIN ensures proper actomyosin-driven maturation of competent endothelial junctions by forming a molecular complex with γ-catenin (also known as junction plakoglobin) and Nm23 (also known as NME1), a nucleoside...

..., and respond to external and internal forces by changing their size and signaling activity. However, this mechanosensitivity is still poorly understood at the molecular level. Here, we present direct evidence that actomyosin contractility regulates the molecular kinetics of FAs. We show that the molecular...

... actin bundles. Mechanosensing Stress fibers Zyxin α-actinin Actomyosin contractility Laser nanosurgery Correlative microscopy Viscoelasticity ‡ Author for correspondence (e-mail: [email protected] ) * Present address: Advanced Digital Microscopy, Institute...

... ). ML7 BDM Adhesion-dependent signaling Actomyosin contractility Rho GTPase Reversible arrest © The Company of Biologists Limited 2004 2004 4 3 2004 ‡ Present address: University of Miami School of Medicine, Department of Cell Biology and Anatomy, Miami, FL 33136, USA...