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Keywords: Actin cytoskeleton
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Journal Articles
J Cell Sci jcs.252585.
Published: 15 April 2021
... Biologists Ltd 2021 RACK1 Degranulation Actin cytoskeleton Store-operated calcium entry Mast cell © 2021. Published by The Company of Biologists Ltd. RACK1 plays a critical role in mast cell secretion and calcium mobilization by modulating F-actin dynamics Edismauro G. Freitas Filho1, Elaine Z...
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (3): jcs217356.
Published: 10 February 2021
... cytokines with chemokine-like functions that coordinate a wide spectrum of biological activities, such as migration. Here, we biotin-tagged intracellular MIF/D-DT in vivo to identify important cytosolic interactors and found a plethora of actin cytoskeleton-associated proteins. Although the receptor complex...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (1): jcs247916.
Published: 08 January 2021
..., and thereby, its activities in actin polymerization and polarized growth. Actin cytoskeleton Fungal polarisome Macromolecular assembly Phase separation In the fungi kingdom, polarized cell growth is a dominant behavior underlying various cellular processes, such as budding, for...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (2): jcs241406.
Published: 30 January 2020
... the actin cytoskeleton and its PTMs. Since ∼9% of A. thaliana actin is methylated on His-74 (corresponding to His-73 in animal actin), we desired to establish a system to purify His-74 methylated actin ( Wilkinson et al., 2019 ). To this end, we expressed SETD3 in P. pastoris expressing Ub–A...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (18): jcs213124.
Published: 16 September 2019
... Company of Biologists Ltd 2019 Summary: Cell–cell fusion is promoted by invasive protrusions and mechanosensory responses at the asymmetric fusogenic synapse. Actin cytoskeleton Cell–cell fusion Fusogenic synapse Invasive protrusion Mechanical force Mechanosensory response Myoblast...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (5): jcs232322.
Published: 04 September 2019
... interchangeably examine synaptic actin characteristics, needs careful reconsideration. Actin cytoskeleton Jurkat cells Immune synapse Primary T-cells A healthy actin cytoskeleton is crucial for T-cell function. The actin machinery integrates T-cell receptor (TCR) signalling and biophysical...
Journal Articles
J Cell Sci (2019) 132 (5): jcs220780.
Published: 07 March 2019
...Salma Jalal; Shidong Shi; Vidhyalakshmi Acharya; Ruby Yun-Ju Huang; Virgile Viasnoff; Alexander D. Bershadsky; Yee Han Tee ABSTRACT Actin cytoskeleton self-organization in two cell types, fibroblasts and epitheliocytes, was studied in cells confined to isotropic adhesive islands. In fibroblasts...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (24): jcs218156.
Published: 20 December 2018
.... Published by The Company of Biologists Ltd 2018 Summary: The transmission of mechanical signals through cellular assemblies regulates collective cell behavior. Cell–cell junctions Mechanobiology Actin cytoskeleton Collective cell migration Active matter The ability of metazoan...
Journal Articles
In collection:
Polarity
J Cell Sci (2019) 132 (4): jcs219717.
Published: 13 December 2018
... network contraction via a polarity-sorting mechanism that relies on dwelling of myosins at the plus end of actin filaments. Actin cytoskeleton Actin-myosin contraction Active gel Cell cortex Myosin end-dwelling Polarity sorting Cells have the remarkable ability to actively deform...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (1): jcs202390.
Published: 10 January 2018
.... Cells also attached and formed stress fibres in the H pattern, and images were collected and analysed in a similar manner. TIRF microscopy was used to detect interactions between PAWS1 as well as CD2AP and the actin cytoskeleton at the plasma membrane. Cells were plated in World Precision...
Includes: Supplementary data
Journal Articles
In collection:
Imaging
J Cell Sci (2017) 130 (22): 3801–3808.
Published: 15 November 2017
... interstitial migration in vivo . While neutrophils are classic amoeboid cells, macrophages have a distinct morphology and use a more mesenchymal mode of migration in zebrafish larvae. Migration Neutrophil Macrophage Microtubule Actin cytoskeleton Zebrafish Macrophages and neutrophils are...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (20): 3517–3531.
Published: 15 October 2017
... (SORBS) proteins reveals that vinexin-α and CAP regulate vinculin behavior depending on the stiffness of the extracellular matrix, while ArgBP2 plays a role in generating greater contractile forces. Vinexin CAP ArgBP2 Focal adhesion Actin cytoskeleton Mechanotransduction Extracellular...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (20): 3427–3435.
Published: 15 October 2017
...Klemens Rottner; Jan Faix; Sven Bogdan; Stefan Linder; Eugen Kerkhoff ABSTRACT The actin cytoskeleton and associated motor proteins provide the driving forces for establishing the astonishing morphological diversity and dynamics of mammalian cells. Aside from functions in protruding and contracting...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (16): 2696–2706.
Published: 15 August 2017
... epicardial development. This function of nonmuscle myosin IIB is critical in the regulation of myocardial proliferation and coronary vessel formation. Nonmuscle myosin IIB Epicardial integrity Epicardial epithelial–mesenchymal transition Actin cytoskeleton The development of a functional...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (6): 1169–1178.
Published: 15 March 2017
...Riko Hatakeyama; Keiko Kono; Satoshi Yoshida ABSTRACT The plasma membrane (PM) is frequently challenged by mechanical stresses. In budding yeast, TORC2-Ypk1/Ypk2 kinase cascade plays a crucial role in PM stress responses by reorganizing the actin cytoskeleton via Rho1 GTPase. However, the molecular...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (2): 344–359.
Published: 15 January 2017
... has conserved functions in integrin receptor recycling and lysosome neutralization. Drosophila WASH Actin cytoskeleton Cell adhesion Lysosome neutralization Macrophages Arp2/3 Wiskott-Aldrich syndrome V-ATPase Integrin The Wiskott-Aldrich syndrome protein (WASP) family of...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (1): 152–163.
Published: 01 January 2017
... changes and then influence tumor cell invasion. Mechanotransduction Rap GTPases Focal adhesions Actin cytoskeleton Talin Vinculin Integrin Summary: Tension applied through 3D matrices directs invasion of tumor cells along the tensional axis. Rap1 senses the tension and polarizes the...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (24): 4455–4465.
Published: 15 December 2016
.... R. and Kinzy , T. G. ( 2005 ). Translation elongation factor 1A is essential for regulation of the actin cytoskeleton and cell morphology . Nat. Struct. Mol. Biol.   12 , 772 - 778 . 10.1038/nsmb979 Gross , S. R. and Kinzy , T. G. ( 2007 ). Improper organization of the...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (21): 4046–4056.
Published: 01 November 2016
.... , Yan , H. , Liu , L. , Ding , M. , Peng , H. B. and Shao , F. ( 2009 ). Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement . Mol. Cell   35 , 841 - 855 . 10.1016/j.molcel.2009.09.004...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (6): 1093–1100.
Published: 15 March 2016
...Keeley L. Mui; Christopher S. Chen; Richard K. Assoian ABSTRACT Cadherins and integrins are intrinsically linked through the actin cytoskeleton and share common signaling molecules. Although mechanosensing by the integrin–actin axis has long been appreciated, a growing body of literature now...