... at the barbed end. In the present study we show that human FHOD1 lacks actin nucleation and elongation capacity, but acts as an actin bundling factor with capping activity toward the filament barbed end. Constitutively active FHOD1 associates with actin filaments in filopodia and lamellipodia at the leading...

... The Company of Biologists Limited 2007 2007 Actin bundling Podosomes Podocytes CMS CD2AP CIN85 Migration Coiled-coil Adapter proteins are involved in the intracellular regulation of diverse signaling events of controlling cellular proliferation, differentiation, trafficking, adhesion...

... sodium phosphate buffer, pH 7.0) as indicated in figure legends. Sedimentation of actin filaments and L-plastin was achieved by high-speed centrifugation at 200,000 g for 30 minutes. To sediment actin bundles, samples were centrifuged for 15 minutes at 12,000 g ( Glenney, Jr et al., 1981...