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Keywords: Abscission
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Journal Articles
J Cell Sci (2021) 134 (11): jcs250902.
Published: 08 June 2021
... localization of KIF14, as well as of chromosome passenger complex. These data indicate that KIF1BP is a CITK interactor involved in midbody maturation and abscission, and suggest that cytokinesis failure may contribute to the microcephaly phenotype observed in GOSHS. * Authors for correspondence...
Includes: Supplementary data
Journal Articles
J Cell Sci jcs.244384.
Published: 27 May 2021
...Nicholas V.G. Iannantuono; Gregory Emery Cytokinesis occurs at the end of mitosis/meiosis wherein the cytoplasms of daughter cells are separated. Prior to abscission, an intercellular bridge containing the remaining furrowing machinery, mitotic spindle and actin cytoskeleton connects the two...
Journal Articles
J Cell Sci (2020) 133 (14): jcs248591.
Published: 24 July 2020
...Sabine A. G. Cuijpers; Edwin Willemstein; Jan G. Ruppert; Daphne M. van Elsland; William C. Earnshaw; Alfred C. O. Vertegaal ABSTRACT Cell division ends when two daughter cells physically separate via abscission, the cleavage of the intercellular bridge. It is not clear how the anti-parallel...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (11): jcs215764.
Published: 11 June 2018
... movement of midbody is independent of the Alix and Shrub abscission regulators, the loss of Gliotactin or Anakonda function impedes both the resolution of the connection between the daughter-neighbour cells and midbody movement. TCJ proteins therefore control an additional step of cytokinesis necessary for...
Includes: Supplementary data
Journal Articles
In collection:
Membrane Trafficking
J Cell Sci (2018) 131 (8): jcs209080.
Published: 26 April 2018
...Alessandro Dema; Francesca Macaluso; Francesco Sgrò; Gaia E. Berto; Federico T. Bianchi; Alessandra A. Chiotto; Gianmarco Pallavicini; Ferdinando Di Cunto; Marta Gai ABSTRACT Abscission is the final step of cytokinesis whereby the intercellular bridge (ICB) linking the two daughter cells is cut...
Includes: Supplementary data
Journal Articles
In collection:
Imaging
J Cell Sci (2017) 130 (3): 637–647.
Published: 01 February 2017
... division, inheritance and abscission in a eukaryotic cell. Extensive mitochondrial branching occurred only along the ventral surface of the parasite, but the mitochondria returned to a tubular form during cytokinesis. Fission of the mitochondrion occurred within the cytoplasmic bridge during the final...
Includes: Supplementary data
Journal Articles
In collection:
Autophagy
J Cell Sci (2016) 129 (20): 3721–3731.
Published: 15 October 2016
...Gholamreza Fazeli; Michaela Trinkwalder; Linda Irmisch; Ann Marie Wehman ABSTRACT In animals, the midbody coordinates the end of cytokinesis when daughter cells separate through abscission. The midbody was thought to be sequestered by macroautophagy, but recent evidence suggests that midbodies are...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (17): 3840–3851.
Published: 01 September 2014
...Elizabeth Faris Crowell; Anne-Lise Gaffuri; Barbara Gayraud-Morel; Shahragim Tajbakhsh; Arnaud Echard ABSTRACT The midbody remnant (MBR) that is generated after cytokinetic abscission has recently attracted a lot of attention, because it might have crucial consequences for cell differentiation and...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (8): 1773–1784.
Published: 15 April 2013
...Sadanori Watanabe; Tihana De Zan; Toshimasa Ishizaki; Shuh Narumiya Summary Cytokinesis is initiated by constriction of the cleavage furrow, and completed with separation of the two daughter cells by abscission. Control of transition from constriction to abscission is therefore crucial for...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (18): 4372–4382.
Published: 15 September 2012
... cytokinesis failure, as well as an accumulation of cytokinetic cells. Time-lapse microscopy on siRNA-treated cells revealed a role for SNX9 subfamily members in progression through the ingression and abscission stages of cytokinesis. Depletion of these three proteins disrupted MRLC S19 localization during...
Includes: Supplementary data
Journal Articles
In collection:
Membrane Trafficking
J Cell Sci (2011) 124 (19): 3199–3207.
Published: 01 October 2011
...Hélia Neto; Gwyn W. Gould The terminal stage of cytokinesis – a process termed abscission – is the severing of the thin intercellular bridge that connects the two daughter cells. Recent work provides new insight into the mechanism by which this microtubule-dense membrane bridge is resolved, and...
Journal Articles
J Cell Sci (2011) 124 (9): 1411–1424.
Published: 01 May 2011
...John A. Schiel; Kristin Park; Mary K. Morphew; Evan Reid; Andreas Hoenger; Rytis Prekeris Cytokinesis and abscission are complicated events that involve changes in membrane transport and cytoskeleton organization. We have used the combination of time-lapse microscopy and correlative high-resolution...
Includes: Multimedia, Supplementary data
Journal Articles
In collection:
Membrane Trafficking
J Cell Sci (2009) 122 (13): 2167–2177.
Published: 01 July 2009
... correspondence (e-mail: juan.martin_serrano@kcl.ac.uk ) © The Company of Biologists Limited 2009 2009 Abscission Cytokinesis ESCRT HIV-1 L-domain Retroviral assembly This article is part of a Minifocus on the ESCRT machinery. For further reading, please see related articles: `The ESCRT...
Journal Articles
J Cell Sci (2006) 119 (14): 3008–3019.
Published: 15 July 2006
... physiological levels of this protein in this location are not crucial for RhoA activation and cytokinesis. In cells overexpressing appropriate N-terminal Ect2 fragments, RhoA and Citron kinase localized to the cleavage furrow and ingression occurred, but abscission failed. This failure could be correlated with...
Includes: Multimedia, Supplementary data