...Snježana Kodba; Agathe Chaigne ABSTRACT Cell division involves separating the genetic material and cytoplasm of a mother cell into two daughter cells. The last step of cell division, abscission, consists of cutting the cytoplasmic bridge, a microtubule-rich membranous tube connecting the two cells...

...Nicholas V. G. Iannantuono; Gregory Emery ABSTRACT Cytokinesis occurs at the end of mitosis/meiosis wherein the cytoplasms of daughter cells are separated. Before abscission, an intercellular bridge containing the remaining furrowing machinery, mitotic spindle and actin cytoskeleton connects...

..., as well as of chromosome passenger complex. These data indicate that KIF1BP is a CITK interactor involved in midbody maturation and abscission, and suggest that cytokinesis failure may contribute to the microcephaly phenotype observed in GOSHS. Goldberg–Shprintzen disease (GOSHS, OMIM 609460...

...Sabine A. G. Cuijpers; Edwin Willemstein; Jan G. Ruppert; Daphne M. van Elsland; William C. Earnshaw; Alfred C. O. Vertegaal ABSTRACT Cell division ends when two daughter cells physically separate via abscission, the cleavage of the intercellular bridge. It is not clear how the anti-parallel...

... the movement of midbody is independent of the Alix and Shrub abscission regulators, the loss of Gliotactin or Anakonda function impedes both the resolution of the connection between the daughter-neighbour cells and midbody movement. TCJ proteins therefore control an additional step of cytokinesis necessary...

...Alessandro Dema; Francesca Macaluso; Francesco Sgrò; Gaia E. Berto; Federico T. Bianchi; Alessandra A. Chiotto; Gianmarco Pallavicini; Ferdinando Di Cunto; Marta Gai ABSTRACT Abscission is the final step of cytokinesis whereby the intercellular bridge (ICB) linking the two daughter cells is cut...

... division, inheritance and abscission in a eukaryotic cell. Extensive mitochondrial branching occurred only along the ventral surface of the parasite, but the mitochondria returned to a tubular form during cytokinesis. Fission of the mitochondrion occurred within the cytoplasmic bridge during the final...

...Gholamreza Fazeli; Michaela Trinkwalder; Linda Irmisch; Ann Marie Wehman ABSTRACT In animals, the midbody coordinates the end of cytokinesis when daughter cells separate through abscission. The midbody was thought to be sequestered by macroautophagy, but recent evidence suggests that midbodies...

...Elizabeth Faris Crowell; Anne-Lise Gaffuri; Barbara Gayraud-Morel; Shahragim Tajbakhsh; Arnaud Echard ABSTRACT The midbody remnant (MBR) that is generated after cytokinetic abscission has recently attracted a lot of attention, because it might have crucial consequences for cell differentiation...

...Sadanori Watanabe; Tihana De Zan; Toshimasa Ishizaki; Shuh Narumiya Summary Cytokinesis is initiated by constriction of the cleavage furrow, and completed with separation of the two daughter cells by abscission. Control of transition from constriction to abscission is therefore crucial...

... of cytokinesis failure, as well as an accumulation of cytokinetic cells. Time-lapse microscopy on siRNA-treated cells revealed a role for SNX9 subfamily members in progression through the ingression and abscission stages of cytokinesis. Depletion of these three proteins disrupted MRLC S19 localization during...

...Hélia Neto; Gwyn W. Gould The terminal stage of cytokinesis – a process termed abscission – is the severing of the thin intercellular bridge that connects the two daughter cells. Recent work provides new insight into the mechanism by which this microtubule-dense membrane bridge is resolved...

...John A. Schiel; Kristin Park; Mary K. Morphew; Evan Reid; Andreas Hoenger; Rytis Prekeris Cytokinesis and abscission are complicated events that involve changes in membrane transport and cytoskeleton organization. We have used the combination of time-lapse microscopy and correlative high-resolution...

... for correspondence (e-mail: [email protected] ) © The Company of Biologists Limited 2009 2009 Abscission Cytokinesis ESCRT HIV-1 L-domain Retroviral assembly This article is part of a Minifocus on the ESCRT machinery. For further reading, please see related articles: `The ESCRT...

... that physiological levels of this protein in this location are not crucial for RhoA activation and cytokinesis. In cells overexpressing appropriate N-terminal Ect2 fragments, RhoA and Citron kinase localized to the cleavage furrow and ingression occurred, but abscission failed. This failure could be correlated...