1-4 of 4
Keywords: AURKA
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (14): jcs256297.
Published: 20 July 2021
..., we show that PCNT-depleted oocytes lack phosphorylated Aurora A (pAURKA) at spindle poles, while overall levels are unaltered. To test aMTOC-associated AURKA function, metaphase II (MII) control (WT) and Tg oocytes were briefly exposed to a specific AURKA inhibitor (MLN8237). Similar defects were...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2018) 131 (24): jcs219923.
Published: 14 December 2018
... to elevated levels of Aurora kinase A (AURKA). We developed an image-based high-throughput screening (HTS) assay using a dual-labeling image analysis strategy that identifies both the cilium and the basal body. By using this strategy, we screened small-molecule compounds for the targeted rescue of cilia...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (6): 1078–1093.
Published: 15 March 2017
...Jing Wang; Kumar Nikhil; Keith Viccaro; Lei Chang; Max Jacobsen; George Sandusky; Kavita Shah ABSTRACT We uncovered a crucial role for the Aurora kinase A (AURKA)–Twist1 axis in promoting epithelial-to-mesenchymal transition (EMT) and chemoresistance in pancreatic cancer. Twist1 is the first EMT...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (2): 364–372.
Published: 15 January 2015
... in ciliary biology is not well understood. Here, we describe an interaction between INPP5E and AURKA, a centrosomal kinase that regulates mitosis and ciliary disassembly, and we show that this interaction is important for the stability of primary cilia. Furthermore, AURKA phosphorylates INPP5E and thereby...
Includes: Supplementary data