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Keywords: ATR and ATM checkpoints
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Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2006) 119 (22): 4644–4649.
Published: 15 November 2006
... A Farnesyltransferase inhibitor DNA double-strand breaks ATR and ATM checkpoints Hutchinson-Gilford progeria syndrome (HGPS) is a severe childhood disease characterized by accelerated aging, which is caused by a de novo point mutation (1824C→T) in the LMNA gene, which encodes lamin A and the splice variant...