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Keywords: ATP production
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Journal Articles
Mitochondrial transfer from cancer-associated fibroblasts increases migration in aggressive breast cancer
Open AccessKayla F. Goliwas, Sarah Libring, Emily Berestesky, Shayan Gholizadeh, Samantha C. Schwager, Andra R. Frost, Thomas R. Gaborski, Jian Zhang, Cynthia A. Reinhart-King
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (14): jcs260419.
Published: 28 July 2023
...), which allow for the exchange of cargo between cell types. CAF mitochondria are an integral cargo component and are sufficient to increase the 3D migration of cancer cells. This cargo transfer results in an increase in mitochondrial ATP production in cancer cells, whereas it has a negligible impact...
Includes: Supplementary data
