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Keywords: AP-1
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Autophagy
J Cell Sci (2016) 129 (21): 4076–4090.
Published: 1 November 2016
...Stephanie Wales Tobin; Dabo Yang; John Girgis; Ali Farahzad; Alexandre Blais; John C. McDermott ABSTRACT Mycocyte enhancer factor 2 (MEF2) and activator protein 1 (AP-1) transcription complexes have been individually implicated in myogenesis, but their genetic interaction has not previously been...
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Imaging
J Cell Sci (2014) 127 (16): 3477–3487.
Published: 15 August 2014
...Jennifer Baltes; Jakob Vejby Larsen; Karthikeyan Radhakrishnan; Constanze Geumann; Manuel Kratzke; Claus Munck Petersen; Peter Schu ABSTRACT Here, we describe altered sorting of sortilin in adipocytes deficient for the σ1B-containing AP-1 complex, leading to the inhibition of adipogenesis. The AP-1...
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J Cell Sci (2011) 124 (9): 1465–1476.
Published: 1 May 2011
..., Montreal, QC H3G 1A6, Canada § Author for correspondence ( [email protected] ) 17 12 2010 © 2011. 2011 Adipocytes AP-1 Bone C/EBPα Fra-1 A reciprocal interaction between bone and energy metabolism has been described, whereby a hormone secreted...
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J Cell Sci (2010) 123 (3): 460–471.
Published: 1 February 2010
... recognizes the cytoplasmic acidic-cluster-dileucine (ACLL) sorting signal of Lerp (lysosomal enzyme receptor protein), a homolog of mammalian mannose 6-phosphate receptors. Moreover, both dGGA and another type of TGN-localized clathrin adaptor, AP-1 (adaptor protein-1 complex), are shown to be involved...
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J Cell Sci (2008) 121 (9): 1495–1505.
Published: 1 May 2008
... liposome tubulation in vitro and had a binding preference for PtdIns(4,5) P 2 . However, contrary to SNX9, which primarily acts in clathrin-mediated endocytosis at the plasma membrane, endogenous SNX18 localized to AP-1- and PACS1-positive endosomal structures, which were devoid of clathrin and resistant...
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J Cell Sci (2007) 120 (9): 1505–1511.
Published: 1 May 2007
[email protected] ; [email protected] 6 3 2007 © The Company of Biologists Limited 2007 2007 Y-box factor ZO-1 ZO-2 Symplekin SAF-B AP-1 Epithelial cells form cellular barriers that separate different tissues and body compartments. This requires that they polarise (i.e. develop...
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J Cell Sci (2006) 119 (17): 3643–3654.
Published: 1 September 2006
... of a dominant-negative mutant of ARF1 induces BFA-like modifications in vimentin morphology. The BFA-dependent changes in vimentin architecture occurred concurrently with the release of the ARF1-regulated adaptor complexes AP-3 and AP-1 from membranes and adaptor redistribution to vimentin networks...
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Journal Articles
J Cell Sci (2005) 118 (9): 1981–1989.
Published: 1 May 2005
...Lore Florin; Nicole Maas-Szabowski; Sabine Werner; Axel Szabowski; Peter Angel In skin, fibroblasts of the connective tissue play a decisive role in epidermal homeostasis and repair by contributing to the regulation of keratinocyte proliferation and differentiation. The AP-1 transcription factor...
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Journal Articles
J Cell Sci (2004) 117 (25): 5965–5973.
Published: 1 December 2004
...Jochen Hess; Peter Angel; Marina Schorpp-Kistner The AP-1 transcription factor is mainly composed of Jun, Fos and ATF protein dimers. It mediates gene regulation in response to a plethora of physiological and pathological stimuli, including cytokines, growth factors, stress signals, bacterial...
Journal Articles
J Cell Sci (2003) 116 (24): 4957–4963.
Published: 15 December 2003
...Emmanuel Vial; Christopher J. Marshall The AP-1 (activator protein-1) complex, which consists of proteins of the Fos and Jun families, is thought to play an important role in the balance between cell proliferation and apoptosis, the response to genotoxic stress and cell transformation. In cells...
Journal Articles
J Cell Sci (2003) 116 (22): 4587–4596.
Published: 15 November 2003
...Jochen Hess; Bettina Hartenstein; Sibylle Teurich; Dirk Schmidt; Marina Schorpp-Kistner; Peter Angel Functional analysis in mice has established an absolute requirement of JunB, a member of the AP-1 transcription factor family, during early embryonic development. To investigate the role of JunB...
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J Cell Sci (2003) 116 (5): 763–771.
Published: 1 March 2003
... clathrin adaptor complex AP-1 has long been thought to mediate anterograde transport from the TGN to endosomes. However, recent studies of AP-1-knockout mice implicate AP-1 in retrograde as well as anterograde transport. The recently identified Golgi-associated,γ-ear-containg, ARF-binding (GGA) proteins...
Journal Articles
J Cell Sci (2002) 115 (4): 679–688.
Published: 15 February 2002
... ) © The Company of Biologists Limited 2002 2002 TRAF TNF IL-1R/TLR NF-κB AP-1 The tumor necrosis factor ( T NF) r eceptor a ssociated f actors (TRAFs) constitute a family of genetically conserved adapter proteins that has been found in mammals(TRAF1-6, see review ( Arch et al...
Journal Articles
J Cell Sci (2001) 114 (24): 4469–4476.
Published: 15 December 2001
... of MPR300 in μ1A-adaptin-deficient fibroblasts, which lack a functional AP-1 clathrin adaptor complex. In μ1A-adaptin-deficient fibroblasts, the homologous MPR46 accumulates in endosomes due to a block in retrograde transport to the trans-Golgi network. The MPR300-mediated endocytosis is markedly enhanced...