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Keywords: 5-Aza-CdR
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Journal Articles

5-Aza-2′-deoxycytidine advances the epithelial–mesenchymal transition of breast cancer cells by demethylating Sipa1 promoter-proximal elements

Open Access
In collection:
Cell biology and disease
Ang Lu, Wei Wang, Shu-Fang Wang-Renault, Brian Z. Ring, Yoshimasa Tanaka, Jun Weng, Li Su
Journal: Journal of Cell Science
J Cell Sci (2020) 133 (9): jcs236125.
https://doi.org/10.1242/jcs.236125
Published: 11 May 2020
... promoter-proximal elements that contained a CpG island and demonstrated that the methylation status of the CpG island was inversely correlated with SIPA1 protein expression in cancer cells. 5-Aza-2′-deoxycytidine (5-Aza-CdR), a DNA methyltransferase inhibitor, promoted the expression of Sipa1 in the MCF7...
View article titled, 5-Aza-2′-deoxycytidine advances the epithelial–mesenchymal transition of breast cancer cells by demethylating Sipa1 promoter-proximal elements
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Includes: Supplementary data