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Keywords: 2D monolayerClose
Canhui Yi, Sook Ling Lai, Chi Man Tsang, Margarita Artemenko, Maggie Kei Shuen Tang, Stella W. Pang, Kwok Wai Lo, Sai Wah Tsao, Alice Sze Tsai Wong
Journal: Journal of Cell Science
J Cell Sci (2021) 134 (16): jcs256461.
Published: 23 August 2021
... these to classical two-dimensional (2D) cultures in various aspects of tumor phenotype and drug responses. Compared to 2D monolayers, the 3D spheroids showed significant increases in migration capacity, stemness characteristics, hypoxia and drug resistance. Co-culture with endothelial cells, which mimics essential...
Includes: Supplementary data