... caused an asynchronous chromosome congression in bmh mutants during metaphase. In summary, this report advances the knowledge on contributions of budding yeast 14-3-3 proteins in chromosome segregation by demonstrating their roles in kinetochore integrity and chromosome congression. The 14-3-3 proteins...

... signaling regulates the phosphorylation-dependent association of plakophilins 1 and 3 (PKP1 and PKP3) with 14-3-3 protein isoforms, and uncover unique and partially antagonistic functions of members of the 14-3-3 family in the regulation of desmosomes. 14-3-3γ associated primarily with cytoplasmic PKP1...

... proteins, we found that 14-3-3 proteins promote the cell-surface expression of heterologously expressed and native K ATP channels. 14-3-3 proteins were detected in physical association with K ATP channels in a pancreatic β-cell line. Our results suggest that the Arg-based signal present in Kir6.2...

... and potential interaction partners of activated PI4KIIIβ are unknown. Here we identify phosphoserine/-threonine binding 14-3-3 proteins as novel regulators of PI4KIIIβ activity downstream of this phosphorylation. The PI4KIIIβ-14-3-3 interaction, evident from GST pulldowns, co-immunoprecipitations...

... biological functions for members of multigene families, like the 14-3-3 protein family. Many organisms contain multiple 14-3-3 isoforms, which play a role in numerous processes, including signalling, cell cycle control and apoptosis. It is still unclear whether these isoforms have specialised biological...

... but not as a means to influence the differentiation state of a cell or a tissue. 14-3-3σ is a member of the 14-3-3 protein family, which is predominantly expressed in epithelial cells (Leffers, 1993). Members of the 14-3-3 family of proteins bind to conserved phosphoserine-containing motifs of many proteins...