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Phillip T. Hawkins
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Journal Articles

The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system

In collection:
Autophagy , Cell biology and disease , Membrane trafficking
Aleksandra Somogyi, Emily D. Kirkham, Emyr Lloyd-Evans, Jincy Winston, Nicholas D. Allen, John J. Mackrill, Karen E. Anderson, Phillip T. Hawkins, Sian E. Gardiner, Helen Waller-Evans, Rebecca Sims, Barry Boland, Cora O'Neill
Journal: Journal of Cell Science
J Cell Sci (2023) 136 (6): jcs259875.
https://doi.org/10.1242/jcs.259875
Published: 21 March 2023
View articletitled, The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system
Open the PDF for The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system in another window
Includes: Supplementary data
Journal Articles

The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P 3

Rachel M. Furlong, Andrew Lindsay, Karen E. Anderson, Phillip T. Hawkins, Aideen M. Sullivan, Cora O'Neill
Journal: Journal of Cell Science
J Cell Sci (2019) 132 (20): jcs233221.
https://doi.org/10.1242/jcs.233221
Published: 22 October 2019
View articletitled, The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P 3
Open the PDF for The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P 3 in another window
Includes: Supplementary data
Journal Articles

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils

George Damoulakis, Laure Gambardella, Kent L. Rossman, Campbell D. Lawson, Karen E. Anderson, Yoshinori Fukui, Heidi C. Welch, Channing J. Der, Len R. Stephens, Phillip T. Hawkins
Journal: Journal of Cell Science
J Cell Sci (2014) 127 (11): 2589–2600.
https://doi.org/10.1242/jcs.153049
Published: 1 June 2014
View articletitled, P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils
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Journal Articles

Two distinct functions for PI3-kinases in macropinocytosis

Oliver Hoeller, Parvin Bolourani, Jonathan Clark, Len R. Stephens, Phillip T. Hawkins, Orion D. Weiner, Gerald Weeks, Robert R. Kay
Journal: Journal of Cell Science
J Cell Sci (2013) 126 (18): 4296–4307.
https://doi.org/10.1242/jcs.134015
Published: 15 September 2013
View articletitled, Two distinct functions for PI3-kinases in macropinocytosis
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Includes: Supplementary data
Journal Articles

ARAP3 is essential for formation of lamellipodia after growth factor stimulation

Sonja Krugmann, Simon Andrews, Len Stephens, Phillip T. Hawkins
Journal: Journal of Cell Science
J Cell Sci (2006) 119 (3): 425–432.
https://doi.org/10.1242/jcs.02755
Published: 1 February 2006
View articletitled, ARAP3 is essential for formation of lamellipodia after growth factor stimulation
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Includes: Supplementary data
Journal Articles

Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase

Trevor R. Jackson, Ira J. Blader, Latanya P. Hammonds-Odie, Christina R. Burga, Frank Cooke, Phillip T. Hawkins, Andrea G. Wolf, Katherine A. Heldman, Anne B. Theibert
Journal: Journal of Cell Science
J Cell Sci (1996) 109 (2): 289–300.
https://doi.org/10.1242/jcs.109.2.289
Published: 1 February 1996
View articletitled, Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase
Open the PDF for Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase in another window