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Paul Saftig
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Journal Articles

The lysosomal lipid transporter LIMP-2 is part of lysosome–ER STARD3-VAPB-dependent contact sites

In collection:
Lipid biology , Membrane trafficking , Organelles
Sönke Rudnik, Saskia Heybrock, Etienne Coyaud, Zizhen Xu, Dante Neculai, Brian Raught, Viola Oorschot, Cecilia Heus, Judith Klumperman, Paul Saftig
Journal: Journal of Cell Science
J Cell Sci (2024) 137 (22): jcs261810.
https://doi.org/10.1242/jcs.261810
Published: 26 November 2024
View article titled, The lysosomal lipid transporter LIMP-2 is part of lysosome–ER STARD3-VAPB-dependent contact sites
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Includes: Supplementary data
Journal Articles

Rab GTPase regulation of phagosome–lysosome fusion is bypassed in the presence of micromolar Ca 2+

In collection:
Membrane trafficking
Julia Becker, Ariane Schleinitz, Christina Hermsen, Sabrina Rappold, Paul Saftig, Andreas Jeschke, Albert Haas
Journal: Journal of Cell Science
J Cell Sci (2023) 136 (9): jcs260806.
https://doi.org/10.1242/jcs.260806
Published: 12 May 2023
View article titled, Rab GTPase regulation of phagosome–lysosome fusion is bypassed in the presence of micromolar Ca 2+
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Includes: Supplementary data
Journal Articles

S-palmitoylation determines TMEM55B-dependent positioning of lysosomes

Sönke Rudnik, Saskia Heybrock, Paul Saftig, Markus Damme
Journal: Journal of Cell Science
J Cell Sci (2022) 135 (5): jcs258566.
https://doi.org/10.1242/jcs.258566
Published: 7 September 2021
View article titled, S-palmitoylation determines TMEM55B-dependent positioning of lysosomes
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Includes: Supplementary data
Journal Articles

Lysosomal storage disorders – challenges, concepts and avenues for therapy: beyond rare diseases

In collection:
Cell biology and disease
André R. A. Marques, Paul Saftig
Journal: Journal of Cell Science
J Cell Sci (2019) 132 (2): jcs221739.
https://doi.org/10.1242/jcs.221739
Published: 16 January 2019
View article titled, Lysosomal storage disorders – challenges, concepts and avenues for therapy: beyond rare diseases
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Journal Articles

The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2

Özlem Demirel, Irina Jan, Dirk Wolters, Judith Blanz, Paul Saftig, Robert Tampé, Rupert Abele
Journal: Journal of Cell Science
J Cell Sci (2012) 125 (18): 4230–4240.
https://doi.org/10.1242/jcs.087346
Published: 15 September 2012
View article titled, The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2
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Includes: Supplementary data
Journal Articles

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site

Sylvain M. Le Gall, Thorsten Maretzky, Priya D. A. Issuree, Xiao-Da Niu, Karina Reiss, Paul Saftig, Rama Khokha, Daniel Lundell, Carl P. Blobel
Journal: Journal of Cell Science
J Cell Sci (2010) 123 (22): 3913–3922.
https://doi.org/10.1242/jcs.069997
Published: 15 November 2010
View article titled, ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site
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Includes: Supplementary data
Journal Articles

The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death

Rosa-Ana González-Polo, Patricia Boya, Anne-Laure Pauleau, Abdelali Jalil, Nathanael Larochette, Sylvie Souquère, Eeva-Liisa Eskelinen, Gérard Pierron, Paul Saftig, Guido Kroemer
Journal: Journal of Cell Science
J Cell Sci (2005) 118 (14): 3091–3102.
https://doi.org/10.1242/jcs.02447
Published: 15 July 2005
View article titled, The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death
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Journal Articles

A role for cathepsin E in the processing of mast-cell carboxypeptidase A

Frida Henningsson, Kenji Yamamoto, Paul Saftig, Thomas Reinheckel, Christoph Peters, Stefan D. Knight, Gunnar Pejler
Journal: Journal of Cell Science
J Cell Sci (2005) 118 (9): 2035–2042.
https://doi.org/10.1242/jcs.02333
Published: 1 May 2005
View article titled, A role for cathepsin E in the processing of mast-cell carboxypeptidase A
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Journal Articles

Role for Rab7 in maturation of late autophagic vacuoles

Stefanie Jäger, Cecilia Bucci, Isei Tanida, Takashi Ueno, Eiki Kominami, Paul Saftig, Eeva-Liisa Eskelinen
Journal: Journal of Cell Science
J Cell Sci (2004) 117 (20): 4837–4848.
https://doi.org/10.1242/jcs.01370
Published: 15 September 2004
View article titled, Role for Rab7 in maturation of late autophagic vacuoles
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Journal Articles

Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation

Friederike Egberts, Michael Heinrich, Jens-Michael Jensen, Supandi Winoto-Morbach, Stephan Pfeiffer, Marc Wickel, Michael Schunck, Judith Steude, Paul Saftig, Ehrhardt Proksch, Stefan Schütze
Journal: Journal of Cell Science
J Cell Sci (2004) 117 (11): 2295–2307.
https://doi.org/10.1242/jcs.01075
Published: 1 May 2004
View article titled, Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation
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Journal Articles

A role for the lysosomal membrane protein LGP85 in the biogenesis and maintenance of endosomal and lysosomal morphology

Toshio Kuronita, Eeva-Liisa Eskelinen, Hideaki Fujita, Paul Saftig, Masaru Himeno, Yoshitaka Tanaka
Journal: Journal of Cell Science
J Cell Sci (2002) 115 (21): 4117–4131.
https://doi.org/10.1242/jcs.00075
Published: 1 November 2002
View article titled, A role for the lysosomal membrane protein LGP85 in the biogenesis and maintenance of endosomal and lysosomal morphology
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