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Miguel C. Seabra
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Journal Articles

Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a

Paolo Sanzà, Richard D. Evans, Deborah A. Briggs, Marta Cantero, Lluis Montoliu, Shyamal Patel, Elena V. Sviderskaya, Aymelt Itzen, Ana C. Figueiredo, Miguel C. Seabra, Alistair N. Hume
Journal: Journal of Cell Science
J Cell Sci (2019) 132 (9): jcs212035.
https://doi.org/10.1242/jcs.212035
Published: 30 April 2019
View articletitled, Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a
Open the PDF for Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a in another window
Includes: Supplementary data
Journal Articles

Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL

Thomas Burgoyne, Marie N. O'Connor, Miguel C. Seabra, Daniel F. Cutler, Clare E. Futter
Journal: Journal of Cell Science
J Cell Sci (2015) 128 (7): 1400–1407.
https://doi.org/10.1242/jcs.164400
Published: 1 April 2015
View articletitled, Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL
Open the PDF for Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL in another window
Includes: Supplementary data
Journal Articles

Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium

Silène T. Wavre-Shapton, Ingrid P. Meschede, Miguel C. Seabra, Clare E. Futter
Journal: Journal of Cell Science
J Cell Sci (2014) 127 (17): 3852–3861.
https://doi.org/10.1242/jcs.154757
Published: 1 September 2014
View articletitled, Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium
Open the PDF for Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium in another window
Includes: Supplementary data
Journal Articles

Expression of OA1 limits the fusion of a subset of MVBs with lysosomes – a mechanism potentially involved in the initial biogenesis of melanosomes

Thomas Burgoyne, Rushee Jolly, Belen Martin-Martin, Miguel C. Seabra, Rosanna Piccirillo, Maria Vittoria Schiaffino, Clare E. Futter
Journal: Journal of Cell Science
J Cell Sci (2014) 127 (3): 700.
https://doi.org/10.1242/jcs.148072
Published: 1 February 2014
View articletitled, Expression of OA1 limits the fusion of a subset of MVBs with lysosomes – a mechanism potentially involved in the initial biogenesis of melanosomes
Open the PDF for Expression of OA1 limits the fusion of a subset of MVBs with lysosomes – a mechanism potentially involved in the initial biogenesis of melanosomes in another window
Journal Articles

Expression of OA1 limits the fusion of a subset of MVBs with lysosomes – a mechanism potentially involved in the initial biogenesis of melanosomes

Thomas Burgoyne, Rushee Jolly, Belen Martin-Martin, Miguel C. Seabra, Rosanna Piccirillo, Maria Vittoria Schiaffino, Clare E. Futter
Journal: Journal of Cell Science
J Cell Sci (2013) 126 (22): 5143–5152.
https://doi.org/10.1242/jcs.128561
Published: 15 November 2013
View articletitled, Expression of OA1 limits the fusion of a subset of MVBs with lysosomes – a mechanism potentially involved in the initial biogenesis of melanosomes
Open the PDF for Expression of OA1 limits the fusion of a subset of MVBs with lysosomes – a mechanism potentially involved in the initial biogenesis of melanosomes in another window
Includes: Supplementary data
Journal Articles

Rab27a-mediated protease release regulates neutrophil recruitment by allowing uropod detachment

Rajesh K. Singh, Wenjia Liao, Dhani Tracey-White, Chiara Recchi, Tanya Tolmachova, Sara M. Rankin, Alistair N. Hume, Miguel C. Seabra
Journal: Journal of Cell Science
J Cell Sci (2012) 125 (7): 1652–1656.
https://doi.org/10.1242/jcs.100438
Published: 1 April 2012
View articletitled, Rab27a-mediated protease release regulates neutrophil recruitment by allowing uropod detachment
Open the PDF for Rab27a-mediated protease release regulates neutrophil recruitment by allowing uropod detachment in another window
Includes: Multimedia, Supplementary data
Journal Articles

Melanosomes at a glance

Christina Wasmeier, Alistair N. Hume, Giulia Bolasco, Miguel C. Seabra
Journal: Journal of Cell Science
J Cell Sci (2008) 121 (24): 3995–3999.
https://doi.org/10.1242/jcs.040667
Published: 15 December 2008
View articletitled, Melanosomes at a glance
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Journal Articles

Rab27a and MyoVa are the primary Mlph interactors regulating melanosome transport in melanocytes

Alistair N. Hume, Dmitry S. Ushakov, Abul K. Tarafder, Michael A. Ferenczi, Miguel C. Seabra
Journal: Journal of Cell Science
J Cell Sci (2007) 120 (17): 3111–3122.
https://doi.org/10.1242/jcs.010207
Published: 1 September 2007
View articletitled, Rab27a and MyoVa are the primary Mlph interactors regulating melanosome transport in melanocytes
Open the PDF for Rab27a and MyoVa are the primary Mlph interactors regulating melanosome transport in melanocytes in another window
Includes: Multimedia, Supplementary data
Journal Articles

Multiple regions contribute to membrane targeting of Rab GTPases

Bassam R. Ali, Christina Wasmeier, Lynn Lamoreux, Molly Strom, Miguel C. Seabra
Journal: Journal of Cell Science
J Cell Sci (2004) 117 (26): 6401–6412.
https://doi.org/10.1242/jcs.01542
Published: 15 December 2004
View articletitled, Multiple regions contribute to membrane targeting of Rab GTPases
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Includes: Supplementary data
Journal Articles

Weibel-Palade bodies recruit Rab27 by a content-driven, maturation-dependent mechanism that is independent of cell type

Matthew J. Hannah, Alistair N. Hume, Monica Arribas, Ross Williams, Lindsay J. Hewlett, Miguel C. Seabra, Daniel F. Cutler
Journal: Journal of Cell Science
J Cell Sci (2003) 116 (19): 3939–3948.
https://doi.org/10.1242/jcs.00711
Published: 1 October 2003
View articletitled, Weibel-Palade bodies recruit Rab27 by a content-driven, maturation-dependent mechanism that is independent of cell type
Open the PDF for Weibel-Palade bodies recruit Rab27 by a content-driven, maturation-dependent mechanism that is independent of cell type in another window