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Douglas A. Lauffenburger
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Journal Articles

Models of signalling networks – what cell biologists can gain from them and give to them

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Kevin A. Janes, Douglas A. Lauffenburger
Journal: Journal of Cell Science
J Cell Sci (2013) 126 (9): 1913–1921.
https://doi.org/10.1242/jcs.112045
Published: 1 May 2013
View articletitled, Models of signalling networks – what cell biologists can gain from them and give to them
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Journal Articles

Mena invasive (Mena INV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer

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Evanthia T. Roussos, Michele Balsamo, Shannon K. Alford, Jeffrey B. Wyckoff, Bojana Gligorijevic, Yarong Wang, Maria Pozzuto, Robert Stobezki, Sumanta Goswami, Jeffrey E. Segall, Douglas A. Lauffenburger, Anne R. Bresnick, Frank B. Gertler, John S. Condeelis
Journal: Journal of Cell Science
J Cell Sci (2011) 124 (13): 2120–2131.
https://doi.org/10.1242/jcs.086231
Published: 1 July 2011
View articletitled, Mena invasive (Mena INV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer
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Includes: Multimedia, Supplementary data
Journal Articles

The heparin-binding domain of HB-EGF mediates localization to sites of cell-cell contact and prevents HB-EGF proteolytic release

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Robin N. Prince, Eric R. Schreiter, Peng Zou, H. Steven Wiley, Alice Y. Ting, Richard T. Lee, Douglas A. Lauffenburger
Journal: Journal of Cell Science
J Cell Sci (2010) 123 (13): 2308–2318.
https://doi.org/10.1242/jcs.058321
Published: 1 July 2010
View articletitled, The heparin-binding domain of HB-EGF mediates localization to sites of cell-cell contact and prevents HB-EGF proteolytic release
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Includes: Supplementary data
Journal Articles

EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation

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Elizabeth J. Joslin, Lee K. Opresko, Alan Wells, H. Steven Wiley, Douglas A. Lauffenburger
Journal: Journal of Cell Science
J Cell Sci (2007) 120 (20): 3688–3699.
https://doi.org/10.1242/jcs.010488
Published: 15 October 2007
View articletitled, EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation
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Includes: Supplementary data
Journal Articles

Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor-necrosis-factor-induced apoptosis

Free
Kathryn Miller-Jensen, Kevin A. Janes, Yun-Ling Wong, Linda G. Griffith, Douglas A. Lauffenburger
Journal: Journal of Cell Science
J Cell Sci (2006) 119 (18): 3788–3798.
https://doi.org/10.1242/jcs.03102
Published: 15 September 2006
View articletitled, Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor-necrosis-factor-induced apoptosis
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Includes: Supplementary data
Journal Articles

Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus

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Lily Y. Koo, Darrell J. Irvine, Anne M. Mayes, Douglas A. Lauffenburger, Linda G. Griffith
Journal: Journal of Cell Science
J Cell Sci (2002) 115 (7): 1423–1433.
https://doi.org/10.1242/jcs.115.7.1423
Published: 1 April 2002
View articletitled, Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus
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Journal Articles

Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture

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Ann E. DeWitt, Jian Ying Dong, H. Steven Wiley, Douglas A. Lauffenburger
Journal: Journal of Cell Science
J Cell Sci (2001) 114 (12): 2301–2313.
https://doi.org/10.1242/jcs.114.12.2301
Published: 15 June 2001
View articletitled, Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture
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Journal Articles

The role of transient ERK2 signals in fibronectin- and insulin-mediated DNA synthesis

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Anand R. Asthagiri, Cynthia A. Reinhart, Alan F. Horwitz, Douglas A. Lauffenburger
Journal: Journal of Cell Science
J Cell Sci (2000) 113 (24): 4499–4510.
https://doi.org/10.1242/jcs.113.24.4499
Published: 15 December 2000
View articletitled, The role of transient ERK2 signals in fibronectin- and insulin-mediated DNA synthesis
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Journal Articles

Cell adhesion and motility depend on nanoscale RGD clustering

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Gargi Maheshwari, Gillian Brown, Douglas A. Lauffenburger, Alan Wells, Linda G. Griffith
Journal: Journal of Cell Science
J Cell Sci (2000) 113 (10): 1677–1686.
https://doi.org/10.1242/jcs.113.10.1677
Published: 15 May 2000
View articletitled, Cell adhesion and motility depend on nanoscale RGD clustering
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Journal Articles

Epidermal growth factor alters fibroblast migration speed and directional persistence reciprocally and in a matrix-dependent manner

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Margaret F. Ware, Alan Wells, Douglas A. Lauffenburger
Journal: Journal of Cell Science
J Cell Sci (1998) 111 (16): 2423–2432.
https://doi.org/10.1242/jcs.111.16.2423
Published: 15 August 1998
View articletitled, Epidermal growth factor alters fibroblast migration speed and directional persistence reciprocally and in a matrix-dependent manner
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Journal Articles

Physical and biochemical regulation of integrin release during rear detachment of migrating cells

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Sean P. Palecek, Anna Huttenlocher, Alan F. Horwitz, Douglas A. Lauffenburger
Journal: Journal of Cell Science
J Cell Sci (1998) 111 (7): 929–940.
https://doi.org/10.1242/jcs.111.7.929
Published: 1 April 1998
View articletitled, Physical and biochemical regulation of integrin release during rear detachment of migrating cells
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Journal Articles

EGF receptor regulation of cell motility: EGF induces disassembly of focal adhesions independently of the motility-associated PLCγ signaling pathway

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Heng Xie, Manuel A. Pallero, Kiran Gupta, Philip Chang, Margaret F. Ware, Walter Witke, David J. Kwiatkowski, Douglas A. Lauffenburger, Joanne E. Murphy-Ullrich, Alan Wells
Journal: Journal of Cell Science
J Cell Sci (1998) 111 (5): 615–624.
https://doi.org/10.1242/jcs.111.5.615
Published: 1 March 1998
View articletitled, EGF receptor regulation of cell motility: EGF induces disassembly of focal adhesions independently of the motility-associated PLCγ signaling pathway
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Journal Articles

Integrin dynamics on the tail region of migrating fibroblasts

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Sean P. Palecek, Christine E. Schmidt, Douglas A. Lauffenburger, Alan F. Horwitz
Journal: Journal of Cell Science
J Cell Sci (1996) 109 (5): 941–952.
https://doi.org/10.1242/jcs.109.5.941
Published: 1 May 1996
View articletitled, Integrin dynamics on the tail region of migrating fibroblasts
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Journal Articles

Migration of individual microvessel endothelial cells: stochastic model and parameter measurement

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Cynthia L. Stokes, Douglas A. Lauffenburger, Stuart K. Williams
Journal: Journal of Cell Science
J Cell Sci (1991) 99 (2): 419–430.
https://doi.org/10.1242/jcs.99.2.419
Published: 1 June 1991
View articletitled, Migration of individual microvessel endothelial cells: stochastic model and parameter measurement
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