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Dennis E. Discher
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Journal Articles

Confinement plus Myosin-II suppression maximizes heritable loss of chromosomes, as revealed by live-cell ChReporters

Brandon H. Hayes, Peter Kuangzheng Zhu, Mai Wang, Charlotte R. Pfeifer, Yuntao Xia, Steven Phan, Jason C. Andrechak, Junhong Du, Michael P. Tobin, Alisya Anlas, Lawrence J. Dooling, Manasvita Vashisth, Jerome Irianto, Michael A. Lampson, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci jcs.260753.
DOI: https://doi.org/10.1242/jcs.260753
Published: 9 May 2023
View article titled, Confinement plus Myosin-II suppression maximizes heritable loss of chromosomes, as revealed by live-cell ChReporters
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Journal Articles

Macrophages show higher levels of engulfment after disruption of cis interactions between CD47 and the checkpoint receptor SIRPα

Brandon H. Hayes, Richard K. Tsai, Lawrence J. Dooling, Siddhant Kadu, Justine Y. Lee, Diego Pantano, Pia L. Rodriguez, Shyamsundar Subramanian, Jae-Won Shin, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (2020) 133 (5): jcs237800.
DOI: https://doi.org/10.1242/jcs.237800
Published: 6 March 2020
View article titled, Macrophages show higher levels of engulfment after disruption of cis interactions between CD47 and the checkpoint receptor SIRPα
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Includes: Supplementary data
Journal Articles

Membrane fluctuations and acidosis regulate cooperative binding of ‘marker of self’ protein CD47 with the macrophage checkpoint receptor SIRPα

Jan Steinkühler, Bartosz Różycki, Cory Alvey, Reinhard Lipowsky, Thomas R. Weikl, Rumiana Dimova, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (2019) 132 (4): jcs216770.
DOI: https://doi.org/10.1242/jcs.216770
Published: 16 July 2018
View article titled, Membrane fluctuations and acidosis regulate cooperative binding of ‘marker of self’ protein CD47 with the macrophage checkpoint receptor SIRPα
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Includes: Supplementary data
Journal Articles

The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue

Joe Swift, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (2014) 127 (14): 3005–3015.
DOI: https://doi.org/10.1242/jcs.149203
Published: 15 July 2014
View article titled, The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue
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Journal Articles

Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells ‘feel’ outside and in?

Amnon Buxboim, Irena L. Ivanovska, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (2010) 123 (3): 297–308.
DOI: https://doi.org/10.1242/jcs.041186
Published: 1 February 2010
View article titled, Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells ‘feel’ outside and in?
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Journal Articles

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

Adam J. Engler, Christine Carag-Krieger, Colin P. Johnson, Matthew Raab, Hsin-Yao Tang, David W. Speicher, Joseph W. Sanger, Jean M. Sanger, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (2008) 121 (22): 3794–3802.
DOI: https://doi.org/10.1242/jcs.029678
Published: 15 November 2008
View article titled, Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
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Includes: Multimedia, Supplementary data
Journal Articles

γ-Sarcoglycan deficiency increases cell contractility, apoptosis and MAPK pathway activation but does not affect adhesion

Maureen A. Griffin, Huisheng Feng, Manorama Tewari, Pedro Acosta, Masataka Kawana, H. Lee Sweeney, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (2005) 118 (7): 1405–1416.
DOI: https://doi.org/10.1242/jcs.01717
Published: 1 April 2005
View article titled, γ-Sarcoglycan deficiency increases cell contractility, apoptosis and MAPK pathway activation but does not affect adhesion
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Journal Articles

Adhesion-contractile balance in myocyte differentiation

Maureen A. Griffin, Shamik Sen, H. Lee Sweeney, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (2004) 117 (24): 5855–5863.
DOI: https://doi.org/10.1242/jcs.01496
Published: 15 November 2004
View article titled, Adhesion-contractile balance in myocyte differentiation
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Includes: Supplementary data
Journal Articles

The nuclear envelope lamina network has elasticity and a compressibility limit suggestive of a molecular shock absorber

Kris Noel Dahl, Samuel M. Kahn, Katherine L. Wilson, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (2004) 117 (20): 4779–4786.
DOI: https://doi.org/10.1242/jcs.01357
Published: 15 September 2004
View article titled, The nuclear envelope lamina network has elasticity and a compressibility limit suggestive of a molecular shock absorber
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Journal Articles

Muscle cell peeling from micropatterned collagen: direct probing of focal and molecular properties of matrix adhesion

Hyun J. Ra, Catherine Picart, Huisheng Feng, H. Lee Sweeney, Dennis E. Discher
Journal: Journal of Cell Science
J Cell Sci (1999) 112 (10): 1425–1436.
DOI: https://doi.org/10.1242/jcs.112.10.1425
Published: 15 May 1999
View article titled, Muscle cell peeling from micropatterned collagen: direct probing of focal and molecular properties of matrix adhesion
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