Issues

Summary: An exploration of the diversity of histone acylations and how these modifications are connected to cellular metabolism, regulate gene expression and are linked to metabolic disorders.

Summary: We present an overview of a mechanism of amino acid sequence-dependent phase separation behaviour of intrinsically disordered proteins based on the novel parameter ‘charge blockiness’.

Summary: Protein aggregation can either induce or mitigate cytotoxicity, depending on the context. Here, studies with aggregates formed by three GFP-linked proteins in yeast suggest that it is cytoprotective.

Summary: The cannabinoid type 1 receptor is stabilised at the axonal surface through interaction of its intracellular helix 9 domain with the endocytic adaptor protein SGIP1.

Highlighted Article: A description of mitosis and cytokinesis in dinoflagellates, which uncovers a new alternative mechanism for cell division, highlighting the plasticity of cell biological processes in eukaryotic cells.

Summary: The Nespin homolog MSP300 plays a role in basal autophagy in Drosophila muscle.

Highlighted Article: Plasmodium berghei S14 is an inner membrane complex-associated protein essential for sporozoite gliding motility and host cell invasion.

Summary: Mammalian mRNA capping enzyme is exported to the cytoplasm where it localizes to stress granules during oxidative stress and protects its substrate mRNAs in the time of cellular recovery from stress.