Skip to Main Content

Advertisement

Skip Nav Destination

Issues

RESEARCH HIGHLIGHTS

STICKY WICKET

CELL SCIENTISTS TO WATCH

OPINION

Summary: We summarize how tumor cells upregulate LPAR4, fibronectin and two fibronectin-binding integrins, α5β1 and αvβ3, to promote stress tolerance, cancer stemness and tumor initiation.

REVIEW

Summary: A Review on the current understanding of MAPK15-related atypical MAPK function and regulation, highlighting how studies in amoeba have provided information on atypical MAPK roles in chemotaxis and gene regulation.

RESEARCH ARTICLES

REVIEW COMMONS TRANSFER

Highlighted Article: Inhibitors of transcription suppress both nuclear bleb formation and stabilization without altering nuclear rigidity, actin compression or actin contraction, suggesting new biophysics for nuclear morphology.

Highlighted Article: Within biomolecular condensates the Wnt pathway regulator axin is N-terminally phosphorylated by CK1α, which impairs axin–tankyrase interaction and protects axin from tankyrase-mediated degradation.

REVIEW COMMONS TRANSFER

Summary: Characterisation of TbSmee1, and subsequent comparison with clathrin depletion, suggests that surface-bound cargo can only enter the trypanosome flagellar pocket when endocytosis is active.

Summary: Vimentin intermediate filaments associate with the trans-Golgi network protein GORAB and provide structural stability to the Golgi complex in mammalian cells.

Summary: A rapid time-resolved proximity biotinylation approach to identify novel candidates that facilitate the export of membrane proteins in the P. falciparum-infected red blood cell.

Highlighted Article: Polyploid cells arise with age through a cell fusion process, leading to a decline in the biomechanical fitness of the fruit fly.

FIRST PERSON

PUBLISHER’S NOTE

CORRECTION

Close Modal

or Create an Account

Close Modal
Close Modal