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REVIEWS

Summary: Quiescence is a dormant cellular state with important roles in biology. In this Review, we examine the metabolic pathways that drive quiescence in models of development and disease progression.

Summary: During autophagy, ATG8 proteins perform crucial functions by interacting with many effector proteins. Post-translational modifications of ATG8 proteins are key to control effector interaction and functions, and are reviewed here.

SHORT REPORT

Summary: Knockout of ErbB genes reveals that the ErbB1 and the ErbB2–ErbB3 complex mediate G1/S progression, and a ligand-independent ErbB2 activity is sufficient for preventing apoptosis at high cell density.

RESEARCH ARTICLES

Summary: Identification of novel regulators of the Wnt pathway that control multiciliated cell formation in the airway epithelium.

REVIEW COMMONS TRANSFER

Summary: The enzyme PIP4K functions as both a sensor and a negative regulator of PI(4,5)P2 synthesis by the closely related PIP5K enzymes, tuning the activity of numerous membrane functions.

Highlighted Article: ATP hydrolysis associated with actin filament dynamics does not contribute significantly to the cytosolic ATP level or ATP/ADP ratio in embryonic sensory neuron growth cones, the sites of highest actin dynamics.

Summary: Yeast Aurora B (Ipl1) is recruited to metaphase centromeres under low tension, dependent on Bub1.

Summary: Using CRISPR/Cas9-edited Chlamydomonas mutants, we show that the glutamate-rich regions of the C-terminal tails of α- and β-tubulin are essential for ciliary motility and assembly.

Summary: The plasma membrane at focal adhesions has a locally distinct lipid composition compared to bulk plasma membrane. It has a higher content of cholesterol and phosphatidylcholine with saturated acyl chain.

Summary: Trunk neural crest cell migration and fate decisions rely on glucose oxidation for energy production and mobilize multiple cooperating metabolic pathways for their biosynthetic needs and execution of gene programs.

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