Issues
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Cover image
Cover Image
Cover: Immunofluorescence image of a germarium from Drosophila melanogaster labelled with antibodies against lamin (blue), Mre11 (green, labelling meiotic recombination sites in pro-oocytes) and phosphorylated histone H2Av (at residue S137, red, marking all DNA breaks). Recombination sites corresponding to nascent crossovers persist and relocate to the nuclear periphery of pro-oocytes during mid-pachytene. Brca2–Pds5 complexes regulate the peripheral movement of persistent recombination sites and normal crossover rates. See article by T. Kusch (pp. 717–727).
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In This Issue
Sticky Wicket
Commentaries
Short Reports
Research Articles
Corrections
Articles of Interest in Other COB Journals
From Development
Call for papers - Cilia and Flagella: from Basic Biology to Disease
We are welcoming submissions for our upcoming special issue: Cilia and Flagella: from Basic Biology to Disease. This issue will be coordinated by two Guest Editors: Pleasantine Mill (University of Edinburgh) and Lotte Pedersen (University of Copenhagen). Submission deadline: 1 March 2025.
Biologists @ 100 - join us in Liverpool in March 2025
We are excited to invite you to a unique scientific conference, celebrating the 100-year anniversary of The Company of Biologists, and bringing together our different communities. The conference will incorporate the Spring Meetings of the BSCB and the BSDB, the JEB Symposium Sensory Perception in a Changing World and a DMM programme on antimicrobial resistance. Find out more and register your interest to join us in March 2025 in Liverpool, UK.
Principles and regulation of mechanosensing
Mechanics play a fundamental role in cell physiology and represent physical mechanisms which cells use to influence function from the molecular to tissue scale. In this Review, Stefano Sala and colleagues clearly define mechanosensing and mechanotransduction, illustrate various mechanosensing mechanisms and discuss methods that cells use to regulate these processes.
JCS-FocalPlane Training Grants
Early-career researchers - working in an area covered by JCS - who would like to attend a microscopy training course, please apply. Deadline dates for 2024 applications: 7 September (decision by week commencing 8 October 2024); 22 November (decision by week commencing 16 December).
HIV-1 assembly – when virology meets biophysics
Claire Lacouture and colleagues review mechanisms of assembly of the HIV-1 structural protein Gag from biophysical and biological perspectives. The researchers highlight how HIV-1 Gag hijacks host cell factors associated with cortical actin machinery to make new viral particles.