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Volume 127, Issue 8
April 2014
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    Cover Image

    issue cover

    Cover: Image of an N-cadherin expressing cell grown on an Ncad–Fc-coated surface. EB1–GFP-labelled microtubule plus ends (green) avoid cadherin adhesions (red), which were stained for β-catenin. See article by P. Plestant et al. (pp. 1660–1671).

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  • PDF Icon PDF LinkTable of contents
ISSN 0021-9533
EISSN 1477-9137

COMMENTARY

Chromophore-assisted laser inactivation – towards a spatiotemporal–functional analysis of proteins, and the ablation of chromatin, organelle and cell function
Yukimi Sano,Wataru Watanabe,Sachihiro Matsunaga
View articletitled, Chromophore-assisted laser inactivation – towards a spatiotemporal–functional analysis of proteins, and the ablation of chromatin, organelle and cell function
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SHORT REPORT

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion
Guoliang Fang,Dachuan Zhang,Huilong Yin,Lu Zheng,Xiaolin Bi,Li Yuan
View articletitled, Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion
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CIIA negatively regulates the Ras–Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1
Hyun Sub Hwang,Sang Gil Hwang,Kyoung-Wan Yoon,Je-Hyun Yoon,Kyung-Hye Roh,Eui-Ju Choi
View articletitled, CIIA negatively regulates the Ras–Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1
Supplementary information
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RESEARCH ARTICLE

Regulation of the phosphorylation and nuclear import and export of β-catenin by APC and its cancer-related truncated form
Lili Wang,Xiaoyong Liu,Ekaterina Gusev,Chuanxin Wang,François Fagotto
View articletitled, Regulation of the phosphorylation and nuclear import and export of β-catenin by APC and its cancer-related truncated form
Supplementary information
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Adhesive interactions of N-cadherin limit the recruitment of microtubules to cell–cell contacts through organization of actomyosin
Charlotte Plestant,Pierre-Olivier Strale,Rima Seddiki,Emmanuelle Nguyen,Benoit Ladoux,René-Marc Mège
View articletitled, Adhesive interactions of N-cadherin limit the recruitment of microtubules to cell–cell contacts through organization of actomyosin
Supplementary information
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Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression
Alexandra E. German,Tadanori Mammoto,Elisabeth Jiang,Donald E. Ingber,Akiko Mammoto
View articletitled, Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression
Supplementary information
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Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1
James B. Reinecke,Dawn Katafiasz,Naava Naslavsky,Steve Caplan
View articletitled, Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1
Supplementary information
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RAGE signaling deficiency in rhabdomyosarcoma cells causes upregulation of PAX7 and uncontrolled proliferation
Francesca Riuzzi,Guglielmo Sorci,Roberta Sagheddu,Angelo Sidoni,Rita Alaggio,Vito Ninfo,Rosario Donato
View articletitled, RAGE signaling deficiency in rhabdomyosarcoma cells causes upregulation of PAX7 and uncontrolled proliferation
Supplementary information
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SNARE-dependent interaction of Src, EGFR and β1 integrin regulates invadopodia formation and tumor cell invasion
Karla C. Williams,Marc G. Coppolino
View articletitled, SNARE-dependent interaction of Src, EGFR and β<sub>1</sub> integrin regulates invadopodia formation and tumor cell invasion
Supplementary information
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Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells
Petra Jakobs,Sebastian Exner,Sabine Schürmann,Ute Pickhinke,Shyam Bandari,Corinna Ortmann,Sabine Kupich,Philipp Schulz,Uwe Hansen,Daniela G. Seidler,Kay Grobe
View articletitled, Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells
Supplementary information
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STAT3 and MCL-1 associate to cause a mesenchymal epithelial transition
A. P. Renjini,Shiny Titus,Prashanth Narayan,Megha Murali,Rajesh Kumar Jha,Malini Laloraya
View articletitled, STAT3 and MCL-1 associate to cause a mesenchymal epithelial transition
Supplementary information
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Mutations in Cx30 that are linked to skin disease and non-syndromic hearing loss exhibit several distinct cellular pathologies
Amy C. Berger,John J. Kelly,Patrick Lajoie,Qing Shao,Dale W. Laird
View articletitled, Mutations in Cx30 that are linked to skin disease and non-syndromic hearing loss exhibit several distinct cellular pathologies
Supplementary information
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A cascade of ER exit site assembly that is regulated by p125A and lipid signals
David Klinkenberg,Kimberly R. Long,Kuntala Shome,Simon C. Watkins,Meir Aridor
View articletitled, A cascade of ER exit site assembly that is regulated by p125A and lipid signals
Supplementary information
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α-Catenin cytomechanics – role in cadherin-dependent adhesion and mechanotransduction
Adrienne K. Barry,Hamid Tabdili,Ismaeel Muhamed,Jun Wu,Nitesh Shashikanth,Guillermo A. Gomez,Alpha S. Yap,Cara J. Gottardi,Johan de Rooij,Ning Wang,Deborah E. Leckband
View articletitled, α-Catenin cytomechanics – role in cadherin-dependent adhesion and mechanotransduction
Supplementary information
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Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies
Zi-Jie Chen,Wan-Ping Wang,Yu-Ching Chen,Jing-Ya Wang,Wen-Hsin Lin,Lin-Ai Tai,Gan-Guang Liou,Chung-Shi Yang,Ya-Hui Chi
View articletitled, Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies
Supplementary information
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Fluctuation of Rac1 activity is associated with the phenotypic and transcriptional heterogeneity of glioma cells
Hiroko Yukinaga,Clara Shionyu,Eishu Hirata,Kumiko Ui-Tei,Takeshi Nagashima,Shinji Kondo,Mariko Okada-Hatakeyama,Honda Naoki,Michiyuki Matsuda
View articletitled, Fluctuation of Rac1 activity is associated with the phenotypic and transcriptional heterogeneity of glioma cells
Supplementary information
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CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex
Christoph Datler,Evangelos Pazarentzos,Anne-Laure Mahul-Mellier,Wanwisa Chaisaklert,Ming-Shih Hwang,Foy Osborne,Stefan Grimm
View articletitled, CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex
Supplementary information
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Src kinases and ERK activate distinct responses to Stitcher receptor tyrosine kinase signaling during wound healing in Drosophila
Vasilios Tsarouhas,Liqun Yao,Christos Samakovlis
View articletitled, Src kinases and ERK activate distinct responses to Stitcher receptor tyrosine kinase signaling during wound healing in <em>Drosophila</em>
Supplementary information
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Non-muscle Mlck is required for β-catenin- and FoxO1-dependent downregulation of Cldn5 in IL-1β-mediated barrier dysfunction in brain endothelial cells
Richard S. Beard, Jr,Ricci J. Haines,Kevin Y. Wu,Jason J. Reynolds,Stephanie M. Davis,John E. Elliott,Nikolay L. Malinin,Victor Chatterjee,Byeong J. Cha,Mack H. Wu,Sarah Y. Yuan
View articletitled, Non-muscle Mlck is required for β-catenin- and FoxO1-dependent downregulation of Cldn5 in IL-1β-mediated barrier dysfunction in brain endothelial cells
Supplementary information
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IN THIS ISSUE

α-Catenin in mechanotransduction
View articletitled, α-Catenin in mechanotransduction
p125A – lipid sensor for ER exit site assembly
View articletitled, p125A – lipid sensor for ER exit site assembly
Microtubules in cadherin-based adhesion
View articletitled, Microtubules in cadherin-based adhesion
Connexin 30 disease mechanisms
View articletitled, Connexin 30 disease mechanisms
CKMT1 – gatekeeper of mitochondrial permeability transition
View articletitled, CKMT1 – gatekeeper of mitochondrial permeability transition

ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT
Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination
Linde Kegel,Martine Jaegle,Siska Driegen,Eerik Aunin,Kris Leslie,Yuko Fukata,Masahiko Watanabe,Masaki Fukata,Dies Meijer
View articletitled, Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination
Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis
Claudia Korn,Beate Scholz,Junhao Hu,Kshitij Srivastava,Jessica Wojtarowicz,Tabea Arnsperger,Ralf H. Adams,Michael Boutros,Hellmut G. Augustin,Iris Augustin
View articletitled, Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis
Accepted manuscripts
Optogenetically engineered Ca 2+ oscillation-mediated DRP1 activation promotes mitochondrial fission and cell death
Yi-Shyun Lai, Cheng-Chi Chang, Yong-Yi Chen, Thi My Hang Nguyen, Jixuan Xu, Ying-Chi Chen, Yu-Fen Chang, Chia-Yih Wang, Pai-Sheng Chen, Shih-Chieh Lin, I-Chen Peng, Shaw-Jenq Tsai, Wen-Tai Chiu
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick Caswell
Development of a fluorescence reporter system to quantify transcriptional activity of endogenous p53 in living cells
Tatsuki Tsuruoka, Emiri Nakayama, Takuya Endo, Shingo Harashima, Rui Kamada, Kazuyasu Sakaguchi, Toshiaki Imagawa
Cik1 and Vik1 Accessory Proteins Confer Distinct Functions to the Kinesin-14, Kar3
Zane J. Bergman, Jonathan J. Wong, David G. Drubin, Georjana Barnes
Radial spoke protein 9 is necessary for axoneme assembly in Plasmodium but not in trypanosomatid parasites
Chandra Ramakrishnan, Cécile Fort, Sara Rute Marques, David J. P. Ferguson, Marion Gransagne, Jake Baum, Soraya Chaouch, Elisabeth Mouray, Linda Kohl, Richard J. Wheeler, Robert E. Sinden
More accepted manuscripts

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