Cover: Image of an N-cadherin expressing cell grown on an Ncad–Fc-coated surface. EB1–GFP-labelled microtubule plus ends (green) avoid cadherin adhesions (red), which were stained for β-catenin. See article by P. Plestant et al. (pp. 1660–1671).
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Chromophore-assisted laser inactivation – towards a spatiotemporal–functional analysis of proteins, and the ablation of chromatin, organelle and cell function
Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion
CIIA negatively regulates the Ras–Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1
Regulation of the phosphorylation and nuclear import and export of β-catenin by APC and its cancer-related truncated form
Adhesive interactions of N-cadherin limit the recruitment of microtubules to cell–cell contacts through organization of actomyosin
Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression
Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1
RAGE signaling deficiency in rhabdomyosarcoma cells causes upregulation of PAX7 and uncontrolled proliferation
SNARE-dependent interaction of Src, EGFR and β1 integrin regulates invadopodia formation and tumor cell invasion
Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells
STAT3 and MCL-1 associate to cause a mesenchymal epithelial transition
Mutations in Cx30 that are linked to skin disease and non-syndromic hearing loss exhibit several distinct cellular pathologies
A cascade of ER exit site assembly that is regulated by p125A and lipid signals
α-Catenin cytomechanics – role in cadherin-dependent adhesion and mechanotransduction
Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies
Fluctuation of Rac1 activity is associated with the phenotypic and transcriptional heterogeneity of glioma cells
CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex
Src kinases and ERK activate distinct responses to Stitcher receptor tyrosine kinase signaling during wound healing in Drosophila
Non-muscle Mlck is required for β-catenin- and FoxO1-dependent downregulation of Cldn5 in IL-1β-mediated barrier dysfunction in brain endothelial cells
IN THIS ISSUE
ARTICLE OF INTEREST IN OTHER COB JOURNALS
Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination
Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis
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