Issues
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Cover image
Cover Image
Cover: Immunofluorescent staining of CFTR (green) in the proximal mouse epididymis. In addition to being located in the apical membrane, CFTR is localised at tight junctions, where it uses its PDZ-binding domain to interact with ZO-1. Through this interaction, CFTR mediates the transcription of genes that control differentiation and proliferation, which it modulates by regulating the retention or recruitment of ZO-1 nucleic acid binding protein (ZONAB; also known as YBX3) to tight junctions. Blue, DAPI. See article by Ye Chun Ruan et al. (pp. 4396–4408).
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In This Issue
Commentaries
Short Report
Research Articles
Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network
Articles of Interest in Other COB Journals
JCS fast-track option

Have a paper that has been reviewed elsewhere? JCS is pleased to consider such manuscripts for fast-tracked decision making. Send us your manuscript together with the full set of reviews and decision letters, and we will make an initial decision within one week.
Special Issue – Cell Biology of Mitochondria

Our special issue on ‘Cell Biology of Mitochondria’ is now complete. Explore this issue and read the Editorial from our Guest Editors Ana J. García-Sáez and Heidi McBride.
Save the date – Imaging Cell Dynamics

We are delighted to announce that we will be hosting a 2026 Imaging Cell Dynamics meeting. This meeting will provide a unique opportunity to bring together experts working at the interface between cell biology and imaging. Save the date for 11-14 May 2026 and register for more information.
Origin and evolution of mitochondrial inner membrane composition

In this Review, Kailash Venkatraman and colleagues provide an examination of the morphological similarities between prokaryotic intracytoplasmic membranes and mitochondrial inner membranes, and whether cristae evolution has driven specialisation of the mitochondrial lipidome.
Resolution in super-resolution microscopy
Super-resolution microscopy (SRM) has emerged as a powerful tool for biological discovery. In this Perspective, Kirti Prakash and colleagues compile expert opinions on crucial, yet often overlooked, aspects of SRM that are essential for maximising its benefits and advancing the field.