Cover: Localisation of ARHGAP19, a GAP protein acting on RhoA, during mitosis of T lymphocyte. The GFP-tagged nuclear protein ARHGAP19 is released into the cytoplasm at mitosis entry and then relocalises to the polar region of the plasma membrane in anaphase. The still is from Movie 2 of the article by M. D. David et al. (pp. 400–410).
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CELL SCIENCE AT A GLANCE
The conserved ciliary protein Bug22 controls planar beating of Chlamydomonas flagella
The tumor suppressor Lgl1 forms discrete complexes with NMII-A and Par6α–aPKCζ that are affected by Lgl1 phosphorylation
Peroxisome proliferator-activated receptor-γ interrupts angiogenic signal transduction by transrepression of platelet-derived growth factor-β receptor in hepatic stellate cells
Phosphorylation of the E3 ubiquitin ligase RNF41 by the kinase Par-1b is required for epithelial cell polarity
Spire-1 contributes to the invadosome and its associated invasive properties
Oncogenic deletion mutants of gp130 signal from intracellular compartments
Arf activation at the Golgi is modulated by feed-forward stimulation of the exchange factor GBF1
PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation
Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast
Light-harvesting chlorophyll pigments enable mammalian mitochondria to capture photonic energy and produce ATP
The RhoGAP ARHGAP19 controls cytokinesis and chromosome segregation in T lymphocytes
The Smad7–Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-β
Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis
Live-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis
Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis
Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size
Specification of leading and trailing cell features during collective migration in the Drosophila trachea
MicroRNA-141-3p plays a role in human mesenchymal stem cell aging by directly targeting ZMPSTE24
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