Issues
-
Cover image
Cover Image
Cover: Ubiquitylation regulates numerous cellular functions, including autophagy. Shown here are MCF-7 breast adenocarcinoma cells, stably expressing a GFP-tagged autophagy receptor (green), that have been subjected to amino acid starvation plus bafilomycin A1 treatment to maximise autophagy flux and block substrate degradation. Cells were stained with antibodies against the early endosomal antigen-1 (EEA1) (blue) and p62 (SQSTM1) (red). For an overview of different ubiquitin functions, see our Minifocus starting on page 249. Image: David G. McEwan and Ivan Dikic, University of Frankfurt Medical School. - PDF Icon PDF LinkTable of contents
STICKY WICKET
CELL SCIENCE AT A GLANCE
COMMENTARY
SHORT REPORT
RESEARCH ARTICLE
ARTICLE OF INTEREST IN OTHER COB JOURNALS
FROM DEVELOPMENT
IN THIS ISSUE
Interviews with Biologists @ 100 conference speakers

Explore our interviews with keynote speakers from the Biologists @ 100 conference, hosted to celebrate our publisher’s 100th anniversary, where we discuss climate change and biodiversity with Hans-Otto Pörtner and Jane Francis, health and disease with Charles Swanton and Sadaf Farooqi, and emerging technologies with Manu Prakash and Jennifer Lippincott-Schwartz.
Introducing our new Associate Editors

In this Editorial, JCS Editor-in-Chief Michael Way welcomes five new Associate Editors to the JCS team. These Associate Editors will expand our support for the wider cell biology community and handle articles in immune cell biology, proteostasis, imaging and image analysis, plant cell biology, and stem cell biology and modelling.
The spatial choreography of mRNA biosynthesis

In their Review, André Ventura-Gomes and Maria Carmo-Fonseca detail the latest research progress and technological advancements that are helping to unlock how nuclear organisation underpins control of gene transcription and pre-mRNA splicing.
JCS-FocalPlane Training Grants

Early-career researchers - working in an area covered by JCS - who would like to attend a microscopy training course, please apply. Deadline dates for 2025 applications: 6 June 2025 (decision by week commencing 28 July 2025) and 5 September 2025 (decision by week commencing 20 October 2025).
The emerging roles of the endoplasmic reticulum in mechanosensing and mechanotransduction

In their Review, Jonathan Townson and Cinzia Progida highlight recently emerging evidence for a role of the endoplasmic reticulum in enabling a cell to sense and respond to changes in the extracellular mechanical environment.