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Issues

Volume 125, Issue 15
August 2012
Journal of Cell Science Cover Image for Volume 125, Issue 15
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  • Cover image

    Cover Image

    issue cover

    Cover: The central spindle microtubule bundle formed between segregating chromosomes in anaphase of the first division of a C. elegans embryo visualised by immunofluorescence (magenta, microtubules; blue, DNA). The microtubulebundling protein PRC1 (green) cooperates with several factors to organise a robust central spindle that is important for cytokinesis. See article by Kian-Yong Lee et al. (pp. 3495–3500).

  • PDF Icon PDF LinkTable of contents
ISSN 0021-9533
EISSN 1477-9137

CELL SCIENCE AT A GLANCE

Cytokinesis microtubule organisers at a glance
Kian-Yong Lee,Tim Davies,Masanori Mishima
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COMMENTARY

The in vivo function of mammalian cell and tissue polarity regulators – how to shape and maintain the epidermal barrier
Michaela T. Niessen,Sandra Iden,Carien M. Niessen
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Structure and function of endosomes in plant cells
Anthony L. Contento,Diane C. Bassham
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Actin nucleators in the nucleus: an emerging theme
Louise Weston,Amanda S. Coutts,Nicholas B. La Thangue
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SHORT REPORT

BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
J. Ross Chapman,Alex J. Sossick,Simon J. Boulton,Stephen P. Jackson
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RESEARCH ARTICLE

The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels
Nina Peel,Michael Dougherty,Jacqueline Goeres,Yan Liu,Kevin F. O'Connell
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The MARVEL transmembrane motif of occludin mediates oligomerization and targeting to the basolateral surface in epithelia
Yakey Yaffe,Jeanne Shepshelovitch,Inbar Nevo-Yassaf,Adva Yeheskel,Hedva Shmerling,Joanna M. Kwiatek,Katharina Gaus,Metsada Pasmanik-Chor,Koret Hirschberg
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Grb2 mediates semaphorin-4D-dependent RhoA inactivation
Tianliang Sun,Rameshkumar Krishnan,Jakub M. Swiercz
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Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization
Junfeng Bi,Yanhui Xiang,Haiyang Chen,Zhonghua Liu,Sebastian Grönke,Ronald P. Kühnlein,Xun Huang
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Abp1 utilizes the Arp2/3 complex activator Scar/WAVE in bristle development
Nicole Koch,Elavarasi Dharmalingam,Martin Westermann,Britta Qualmann,Ulrich Thomas,Michael M. Kessels
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Regulation of multiple target genes by miR-1 and miR-206 is pivotal for C2C12 myoblast differentiation
Katarzyna Goljanek-Whysall,Helio Pais,Tina Rathjen,Dylan Sweetman,Tamas Dalmay,Andrea Münsterberg
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Restructured endoplasmic reticulum generated by mutant amyotrophic lateral sclerosis-linked VAPB is cleared by the proteasome
Giulia Papiani,Annamaria Ruggiano,Matteo Fossati,Andrea Raimondi,Giovanni Bertoni,Maura Francolini,Roberta Benfante,Francesca Navone,Nica Borgese
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TRC40 can deliver short secretory proteins to the Sec61 translocon
Nicholas Johnson,Fabio Vilardi,Sven Lang,Pawel Leznicki,Richard Zimmermann,Stephen High
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Presynaptic PI3K activity triggers the formation of glutamate receptors at neuromuscular terminals of Drosophila
Sheila Jordán-Álvarez,Wernher Fouquet,Stephan J. Sigrist,Angel Acebes
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SUMOylation of HNF4α regulates protein stability and hepatocyte function
Wenli Zhou,Zara Hannoun,Ellis Jaffray,Claire N. Medine,James R. Black,Sebastian Greenhough,Liang Zhu,James A. Ross,Stuart Forbes,Ian Wilmut,John P. Iredale,Ronald T. Hay,David C. Hay
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Nuclear p120 catenin unlocks mitotic block of contact-inhibited human corneal endothelial monolayers without disrupting adherent junctions
Ying-Ting Zhu,Hung-Chi Chen,Szu-Yu Chen,Scheffer C. G. Tseng
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COPI-mediated membrane trafficking is required for cytokinesis in Drosophila male meiotic divisions
Daishi Kitazawa,Masamitsu Yamaguchi,Hajime Mori,Yoshihiro H. Inoue
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N-cadherin-mediated cell–cell adhesion promotes cell migration in a three-dimensional matrix
Wenting Shih,Soichiro Yamada
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Association of bromodomain BET proteins with chromatin requires dimerization through the conserved motif B
Pablo Garcia-Gutierrez,Maria Mundi,Mario Garcia-Dominguez
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The maize (Zea mays) desynaptic (dy) mutation defines a pathway for meiotic chromosome segregation, linking nuclear morphology, telomere distribution and synapsis
Shaun P. Murphy,Hank W. Bass
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ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT
Hh signalling is essential for somatic stem cell maintenance in the Drosophila testis niche
Marcus Michel,Adam P. Kupinski,Isabel Raabe
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Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing
Faizaan Mohammad,Gaurav Kumar Pandey,Tanmoy Mondal,Stefan Enroth,Lisa Redrup,Ulf Gyllensten,Chandrasekhar Kanduri
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IN THIS ISSUE

Eyeing up HCEC proliferation
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TRC40 routes secretory proteins to the ER
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Abp1 sets bristles straight
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Perilipins: moving fat
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Grb2 fills semaphorin (Rho)GAP
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N-cadherin and cell migration
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Accepted manuscripts
Approaches to reduce succinate accumulation by restoration of succinate dehydrogenase activity in cultured adrenal cells
Fatimah Al Khazal, Leili Rahimi, Fan Feng, Nicole A. Becker, Clifford D. Folmes, Judith Favier, L. James Maher
Med12 cooperates with multiple differentiation signals to facilitate efficient lineage transitions in embryonic stem cells
Max Fernkorn, Christian Schröter
The P4-phospholipid flippase Atp11a is required for maintenance of eye and ear structure in zebrafish
Alexia Hawkey-Noble, Cameron Tobin, Muhammad Ameen, Liam Osmond, Colby Gill, Christina S. Bottaro, Terry-Lynn Young, Curtis R. French
Spatial regulation of mitochondrial membrane potential by 𝛂5ꞵ1 integrin engagement in collective cell migration
Gustavo G. Pacheco, Bette J. Dzamba, Wakako Endo, Benjamin C. Edwards, Minah Khan, Tien Comlekoglu, David R. Shook, Keri Quasey, Maureen A. Bjerke, Glen D. Hirsh, David F. Kashatus, Douglas W. DeSimone
NHR-85 modulates mitochondrial and lipid homeostasis to protect against α-synuclein aggregation in C. elegans
Dikaia Tsagkari, Maria Markaki, Nektarios Tavernarakis
More accepted manuscripts

Interviews with Biologists @ 100 conference speakers

Explore our interviews with keynote speakers from the Biologists @ 100 conference, hosted to celebrate our publisher’s 100th anniversary, where we discuss climate change and biodiversity with Hans-Otto Pörtner and Jane Francis, health and disease with Charles Swanton and emerging technologies with Manu Prakash and Jennifer Lippincott-Schwartz.

Introducing our new Associate Editors

In this Editorial, JCS Editor-in-Chief Michael Way welcomes five new Associate Editors to the JCS team. These Associate Editors will expand our support for the wider cell biology community and handle articles in immune cell biology, proteostasis, imaging and image analysis, plant cell biology, and stem cell biology and modelling.

The spatial choreography of mRNA biosynthesis

In their Review, André Ventura-Gomes and Maria Carmo-Fonseca detail the latest research progress and technological advancements that are helping to unlock how nuclear organisation underpins control of gene transcription and pre-mRNA splicing.

JCS-FocalPlane Training Grants

Supporting microcopy training for early-career researchers in cell biology - apply for a grant up to £1,000

Early-career researchers - working in an area covered by JCS - who would like to attend a microscopy training course, please apply. Deadline dates for 2025 applications: 6 June 2025 (decision by week commencing 28 July 2025) and 5 September 2025 (decision by week commencing 20 October 2025).

The emerging roles of the endoplasmic reticulum in mechanosensing and mechanotransduction

In their Review, Jonathan Townson and Cinzia Progida highlight recently emerging evidence for a role of the endoplasmic reticulum in enabling a cell to sense and respond to changes in the extracellular mechanical environment.

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