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Volume 123, Issue 20

October 2010

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Cover image

Cover Image

Cover: Live cell image of growing microtubule plus ends in a dividing HeLa cell that stably expresses EB3-GFP. Three consecutive frames obtained at 2.5-second intervals, were colorized in a custom-made plug-in for ImageJ. The frames were obtained by using a Nikon-based Yokogawa spinning disc microscope at a resolution of 67 nm in 1 pixel and an exposure time of 0.5 seconds. The image was composed by Ilya Grigoriev (Erasmus Medical Center, Rotterdam, The Netherlands). See article by A. Akhmanova and M. O. Steinmetz (pp. 3415-3419).
Table of contents

ISSN 0021-9533

EISSN 1477-9137

In this issue

CELL SCIENCE AT A GLANCE
COMMENTARY
RESEARCH ARTICLE
ERRATUM
ARTICLE OF INTEREST IN OTHER COB JOURNALS
- FROM DEVELOPMENT
IN THIS ISSUE

CELL SCIENCE AT A GLANCE

Microtubule +TIPs at a glance

Anna Akhmanova,Michel O. Steinmetz

Extract

View articletitled, Microtubule +TIPs at a glance

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Kinesins at a glance

Sharyn A. Endow,F. Jon Kull,Honglei Liu

Extract

View articletitled, Kinesins at a glance

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COMMENTARY

Tubulin depolymerization may be an ancient biological motor

J. Richard McIntosh,Vladimir Volkov,Fazly I. Ataullakhanov,Ekaterina L. Grishchuk

Abstract

View articletitled, Tubulin depolymerization may be an ancient biological motor

Supplementary information

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Towards a quantitative understanding of mitotic spindle assembly and mechanics

Alex Mogilner,Erin Craig

Abstract

View articletitled, Towards a quantitative understanding of mitotic spindle assembly and mechanics

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Post-translational modifications of microtubules

Dorota Wloga,Jacek Gaertig

Abstract

View articletitled, Post-translational modifications of microtubules

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RESEARCH ARTICLE

Negative regulation of Drosophila JAK–STAT signalling by endocytic trafficking

Oscar Marino Vidal,Wojciech Stec,Nina Bausek,Elizabeth Smythe,Martin P. Zeidler

Abstract

View articletitled, Negative regulation of Drosophila JAK–STAT signalling by endocytic trafficking

Supplementary information

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Snail1 suppresses TGF-β-induced apoptosis and is sufficient to trigger EMT in hepatocytes

D. Lorena Franco,Jèssica Mainez,Sonia Vega,Patricia Sancho,Miguel M. Murillo,Cristina A. de Frutos,Gaelle del Castillo,Cristina López-Blau,Isabel Fabregat,M. Angela Nieto

Abstract

View articletitled, Snail1 suppresses TGF-β-induced apoptosis and is sufficient to trigger EMT in hepatocytes

Supplementary information

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Syt1p promotes activation of Arl1p at the late Golgi to recruit Imh1p

Kuan-Yu Chen,Pei-Chin Tsai,Jia-Wei Hsu,Hsin-Chia Hsu,Chiung-Ying Fang,Lin-Chun Chang,Yueh-Tso Tsai,Chia-Jung Yu,Fang-Jen S. Lee

Abstract

View articletitled, Syt1p promotes activation of Arl1p at the late Golgi to recruit Imh1p

Supplementary information

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The rotation of cellulose synthase trajectories is microtubule dependent and influences the texture of epidermal cell walls in Arabidopsis hypocotyls

Jordi Chan,Elizabeth Crowell,Magdalena Eder,Grant Calder,Susan Bunnewell,Kim Findlay,Samantha Vernhettes,Herman Höfte,Clive Lloyd

Abstract

View articletitled, The rotation of cellulose synthase trajectories is microtubule dependent and influences the texture of epidermal cell walls in Arabidopsis hypocotyls

Supplementary information

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A role for the dynamin-like protein Vps1 during endocytosis in yeast

Iwona I. Smaczynska-de Rooij,Ellen G. Allwood,Soheil Aghamohammadzadeh,Ewald H. Hettema,Martin W. Goldberg,Kathryn R. Ayscough

Abstract

View articletitled, A role for the dynamin-like protein Vps1 during endocytosis in yeast

Supplementary information

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Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial–mesenchymal transition-like state in breast cancer cells in vitro

Ming-Qing Gao,Baek Gil Kim,Suki Kang,Yoon Pyo Choi,Hangran Park,Kyu Sub Kang,Nam Hoon Cho

Abstract

View articletitled, Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial–mesenchymal transition-like state in breast cancer cells in vitro

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Drosophila I-R hybrid dysgenesis is associated with catastrophic meiosis and abnormal zygote formation

Guillermo A. Orsi,Eric F. Joyce,Pierre Couble,Kim S. McKim,Benjamin Loppin

Abstract

View articletitled, Drosophila I-R hybrid dysgenesis is associated with catastrophic meiosis and abnormal zygote formation

Supplementary information

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PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation

Laure Plantard,Antti Arjonen,John G. Lock,Ghasem Nurani,Johanna Ivaska,Staffan Strömblad

Abstract

View articletitled, PtdIns(3,4,5)P3 is a regulator of myosin-X localization and filopodia formation

Supplementary information

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Rac controls PIP5K localisation and PtdIns(4,5)P₂ synthesis, which modulates vinculin localisation and neurite dynamics

Jonathan R. Halstead,Nicolai E. Savaskan,Iman van den Bout,Francis Van Horck,Amra Hajdo-Milasinovic,Mireille Snell,Willem-Jan Keune,Jean-Paul ten Klooster,Peter L. Hordijk,Nullin Divecha

Abstract

View articletitled, Rac controls PIP5K localisation and PtdIns(4,5)P2 synthesis, which modulates vinculin localisation and neurite dynamics

Supplementary information

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Coactivation of the CLOCK–BMAL1 complex by CBP mediates resetting of the circadian clock

Yool Lee,Jiwon Lee,Ilmin Kwon,Yoshihiro Nakajima,Yoshihiro Ohmiya,Gi Hoon Son,Kun Ho Lee,Kyungjin Kim

Abstract

View articletitled, Coactivation of the CLOCK–BMAL1 complex by CBP mediates resetting of the circadian clock

Supplementary information

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ATF3, an adaptive-response gene, enhances TGFβ signaling and cancer-initiating cell features in breast cancer cells

Xin Yin,Christopher C. Wolford,Yi-Seok Chang,Stephen J. McConoughey,Stephen A. Ramsey,Alan Aderem,Tsonwin Hai

Abstract

View articletitled, ATF3, an adaptive-response gene, enhances TGFβ signaling and cancer-initiating cell features in breast cancer cells

Supplementary information

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Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators

Priyadharsini Nagarajan,Shu Shien Chin,Dan Wang,Song Liu,Satrajit Sinha,Lee Ann Garrett-Sinha

Abstract

View articletitled, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators

Supplementary information

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Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling

Viktor Todorović,Bhushan V. Desai,Melanie J. Schroeder Patterson,Evangeline V. Amargo,Adi D. Dubash,Taofei Yin,Jonathan C. R. Jones,Kathleen J. Green

Abstract

View articletitled, Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling

Supplementary information

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CMF70 is a subunit of the dynein regulatory complex

Zakayi P. Kabututu,Michelle Thayer,Jason H. Melehani,Kent L. Hill

Abstract

View articletitled, CMF70 is a subunit of the dynein regulatory complex

Supplementary information

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The microtubule plus-end localization of Aspergillus dynein is important for dynein–early-endosome interaction but not for dynein ATPase activation

Jun Zhang,Lei Zhuang,Young Lee,Juan F. Abenza,Miguel A. Peñalva,Xin Xiang

Abstract

View articletitled, The microtubule plus-end localization of Aspergillus dynein is important for dynein–early-endosome interaction but not for dynein ATPase activation

Supplementary information

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Neuronal connexin-36 can functionally replace connexin-45 in mouse retina but not in the developing heart

Marina Frank,Britta Eiberger,Ulrike Janssen-Bienhold,Luis Pérez de Sevilla Müller,Antje Tjarks,Jung-Sun Kim,Stefan Maschke,Radoslaw Dobrowolski,Philipp Sasse,Reto Weiler,Bernd K. Fleischmann,Klaus Willecke

Abstract

View articletitled, Neuronal connexin-36 can functionally replace connexin-45 in mouse retina but not in the developing heart

Supplementary information

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ERRATUM

Degradation of an intramitochondrial protein by the cytosolic proteasome

Vian Azzu,Martin D. Brand

Extract

View articletitled, Degradation of an intramitochondrial protein by the cytosolic proteasome

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ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT

Generation of distinct signaling modes via diversification of the Egfr ligand-processing cassette

Tal Rousso,Jeremy Lynch,Shaul Yogev,Siegfried Roth,Eyal D. Schejter,Ben-Zion Shilo

View articletitled, Generation of distinct signaling modes via diversification of the Egfr ligand-processing cassette

Developmental role for ACF1-containing nucleosome remodellers in chromatin organisation

Mariacristina Chioda,Sandra Vengadasalam,Elisabeth Kremmer,Anton Eberharter,Peter B. Becker

View articletitled, Developmental role for ACF1-containing nucleosome remodellers in chromatin organisation

IN THIS ISSUE

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Accepted manuscripts alert

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Accepted manuscripts

Formin 3 stabilizes the cytoskeleton of Drosophila tendon cells, thus enabling them to resist muscle tensile forces

Helena Pissarek, Na Huang, Leanna H. Frasch, Hermann Aberle, Manfred Frasch

A dual-purification system to isolate mitochondrial subpopulations

Corey N. Cunningham, Jonathan G. Van Vranken, Jakeline Larios, Katarina Heyden, Steven P. Gygi, Jared Rutter

An endoplasmic reticulum-associated structure sequesters misassembled FG-Nups to help maintain NPC function

Madison Pletan, Emily Wang, Luke Gohmann, Billy Tsai

Compound screening in human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies

Yuki Ishii, Jessica C. Orr, Marie-Belle El Mdawar, Denise R.Bairros de Pilger, David R. Pearce, Kyren A. Lazarus, Rebecca E. Graham, Marko Z. Nikolić, Robin Ketteler, Neil O. Carragher, Sam M. Janes, Robert E. Hynds

ATG9A vesicles are a subtype of intracellular nanovesicle

Mary Fesenko, Daniel J. Moore, Peyton Ewbank, Elizabeth Courthold, Stephen J. Royle

More accepted manuscripts

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Diversity of microtubule arrays in animal cells at a glance

In this Cell Science at a Glance article, Emma van Grinsven and Anna Akhmanova provide an overview of the diverse microtubule arrays present in differentiated animal cells and discuss how these arrays form and function.

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Issues

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CELL SCIENCE AT A GLANCE

COMMENTARY

RESEARCH ARTICLE

ERRATUM

ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT

IN THIS ISSUE

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