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Issues

Volume 122, Issue 6
March 2009
Journal of Cell Science Cover Image for Volume 122, Issue 6
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  • Cover image

    Cover Image

    Issue cover image
    Cover: In vivo regulation of Ras stability by Wnt/{beta}-catenin signaling in the mouse colon. A cryosection of mouse colon tissue was stained by anti-{beta}-catenin (red) and anti-Pan-Ras (green) antibodies. Nuclei were stained by DAPI (blue). Fluorescent signals were observed and captured with a confocal microscope. See article by S.-E. Kim et al. (pp. 842-848).
  • PDF Icon PDF LinkTable of contents
ISSN 0021-9533
EISSN 1477-9137

JCS PRIZE

2008 Winner: Jennifer Levy
Fiona Watt
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CELL SCIENCE AT A GLANCE

Lipid droplets at a glance
Yi Guo,Kimberly R. Cordes,Robert V. Farese, Jr,Tobias C. Walther
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COMMENTARY

Live-cell microscopy – tips and tools
Melanie M. Frigault,Judith Lacoste,Jody L. Swift,Claire M. Brown
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SHORT REPORT

A product of the bicistronic Drosophila melanogaster gene CG31241, which also encodes a trimethylguanosine synthase, plays a role in telomere protection
Orban Komonyi,Tamas Schauer,Gabor Papai,Peter Deak,Imre M. Boros
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SUMOylation regulates Kv2.1 and modulates pancreatic β-cell excitability
Xiao-Qing Dai,Jelena Kolic,Paolo Marchi,Simonetta Sipione,Patrick E. MacDonald
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Assembly of nuclear pore complexes mediated by major vault protein
Friederike Vollmar,Christian Hacker,René-Peiman Zahedi,Albert Sickmann,Andrea Ewald,Ulrich Scheer,Marie-Christine Dabauvalle
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RESEARCH ARTICLE

Memo is a cofilin-interacting protein that influences PLCγ1 and cofilin activities, and is essential for maintaining directionality during ErbB2-induced tumor-cell migration
Maria Meira,Régis Masson,Igor Stagljar,Susanne Lienhard,Francisca Maurer,Anne Boulay,Nancy E. Hynes
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βPIX-activated Rac1 stimulates the activation of phospholipase D, which is associated with exocytosis in neuroendocrine cells
Fanny Momboisse,Etienne Lonchamp,Valerie Calco,Mara Ceridono,Nicolas Vitale,Marie-France Bader,Stéphane Gasman
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The BTB-MATH protein BATH-42 interacts with RIC-3 to regulate maturation of nicotinic acetylcholine receptors
Anna Shteingauz,Emiliano Cohen,Yoav Biala,Millet Treinin
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Determinants of aquaporin-4 assembly in orthogonal arrays revealed by live-cell single-molecule fluorescence imaging
Jonathan M. Crane,Alan S. Verkman
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Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells
Esther Marza,Karina T. Simonsen,Nils J. Færgeman,Giovanni M. Lesa
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A novel function for the atypical small G protein Rab-like 5 in the assembly of the trypanosome flagellum
Christine Adhiambo,Thierry Blisnick,Géraldine Toutirais,Emmanuelle Delannoy,Philippe Bastin
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H-Ras is degraded by Wnt/β-catenin signaling via β-TrCP-mediated polyubiquitylation
Sung-Eun Kim,Ju-Yong Yoon,Woo-Jeong Jeong,Soung-Hoo Jeon,Yoon Park,Jong-Bok Yoon,Y. N. Park,Hoguen Kim,Kang-Yell Choi
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A novel role for SED1 (MFG-E8) in maintaining the integrity of the epididymal epithelium
Adam S. Raymond,Barry D. Shur
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Flagellar membrane localization via association with lipid rafts
Kevin M. Tyler,Alina Fridberg,Krista M. Toriello,Cheryl L. Olson,John A. Cieslak,Theodore L. Hazlett,David M. Engman
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Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane
Brian T. Emmer,Christina Souther,Krista M. Toriello,Cheryl L. Olson,Conrad L. Epting,David M. Engman
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Huntingtin promotes cell survival by preventing Pak2 cleavage
Shouqing Luo,David C. Rubinsztein
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IN THIS ISSUE

Vaults – giving us pores?
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Getting to grips with GSL function
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How Wnts keep Ras in check
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A role for rafts in flagella
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nAChr maturation: reining in RIC-3
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ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT
Primary cilia regulate Shh activity in the control of molar tooth number
Atsushi Ohazama,Courtney J. Haycraft,Maisa Seppala,James Blackburn,Sarah Ghafoor,Martyn Cobourne,David C. Martinelli,Chen-Ming Fan,Renata Peterkova,Herve Lesot,Bradley K. Yoder,Paul T. Sharpe
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Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation
Nasreen Akhtar,Rebecca Marlow,Elise Lambert,Franziska Schatzmann,Emma T. Lowe,Julia Cheung,Elad Katz,Weiping Li,Chuanyue Wu,Shoukat Dedhar,Matthew J. Naylor,Charles H. Streuli
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Accepted manuscripts
β-Arrestin mediates the export of ciliary GPR161 but not Smoothened together with the BBSome and IFT machinery
Taiju Fujii, Norihito Murai, Shinya Aso, Hiroyuki Takatsu, Hye-Won Shin, Yohei Katoh, Kazuhisa Nakayama
Glutamine modulates stress granule formation in cancer cells through core RNA-binding proteins
Gabriel P. Faber, Gilad Gross, Oz Mualem, Matan Y. Avivi, Hiba Waldman Ben-Asher, Orly Yaron, Orit Shefi, Rakefet Ben-Yishay, Dana Ishay-Ronen, Yaron Shav-Tal
A Cryo-Electron Microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface
Lior Peer, Orly Dym, Nadav Elad, Asa Tirosh, Jossef Jacobovitch, Ehud Sivan, Mor Angel, Shira Albeck, Maya Schuldiner, Yoav Peleg, Einat Zalckvar
A data-driven model for mitochondrial inner membrane remodeling as a driving force of organelle shaping
Noga Preminger, Ben Zucker, Sarah Hassdenteufel, Till Stephan, Stefan Jakobs, Michael M. Kozlov, Maya Schuldiner
LCN2 promotes focal adhesion formation and invasion by stimulating Src activation
Bhagya Shree Choudhary, Nazia Chaudhary, Bushra K. Khan, Aditi Vijan, Dibita Mandal, Leena Pilankar, Shubham Gawand, Prerana Uttankar, Megha Sharma, Anusha Shivashankar, Rinki Doloi, Neha Joshi, Manjula Das, Sorab N. Dalal
More accepted manuscripts

Interviews with Biologists @ 100 conference speakers

Explore our interviews with keynote speakers from the Biologists @ 100 conference, hosted to celebrate our publisher’s 100th anniversary, where we discuss climate change and biodiversity with Hans-Otto Pörtner and Jane Francis, health and disease with Charles Swanton and Sadaf Farooqi, and emerging technologies with Manu Prakash and Jennifer Lippincott-Schwartz.

Introducing our new Associate Editors

In this Editorial, JCS Editor-in-Chief Michael Way welcomes five new Associate Editors to the JCS team. These Associate Editors will expand our support for the wider cell biology community and handle articles in immune cell biology, proteostasis, imaging and image analysis, plant cell biology, and stem cell biology and modelling.

The spatial choreography of mRNA biosynthesis

In their Review, André Ventura-Gomes and Maria Carmo-Fonseca detail the latest research progress and technological advancements that are helping to unlock how nuclear organisation underpins control of gene transcription and pre-mRNA splicing.

JCS-FocalPlane Training Grants

Supporting microcopy training for early-career researchers in cell biology - apply for a grant up to £1,000

Early-career researchers - working in an area covered by JCS - who would like to attend a microscopy training course, please apply. Deadline dates for 2025 applications: 6 June 2025 (decision by week commencing 28 July 2025) and 5 September 2025 (decision by week commencing 20 October 2025).

The emerging roles of the endoplasmic reticulum in mechanosensing and mechanotransduction

In their Review, Jonathan Townson and Cinzia Progida highlight recently emerging evidence for a role of the endoplasmic reticulum in enabling a cell to sense and respond to changes in the extracellular mechanical environment.

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