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Volume 122, Issue 12

June 2009

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Cover image

Cover Image

Cover: Cdk2^−/− mice zygotene spermatocyte with double immunolabelling of the central-element protein SYCP1 (green) and the lateral-element protein SYCP3 (red) of the synaptonemal complex. Pairing defects and heterologous synapsis are evident. Single unsynapsed SYCP3-labelled lateral elements can be observed running between different synapsed regions (yellow). See article by A. Viera et al. (pp. 2149-2159).
Table of contents

ISSN 0021-9533

EISSN 1477-9137

In this issue

STICKY WICKET
CELL SCIENCE AT A GLANCE
OPINION
COMMENTARY
SPECKLE MICROSCOPY UPDATES
SHORT REPORT
RESEARCH ARTICLE
ARTICLE OF INTEREST IN OTHER COB JOURNALS
- FROM DEVELOPMENT
IN THIS ISSUE

STICKY WICKET

Supplemental Siberia I – into the cold

Mole

Extract

View articletitled, Supplemental Siberia I – into the cold

Supplementary information

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CELL SCIENCE AT A GLANCE

mRNA nuclear export at a glance

Sean R. Carmody,Susan R. Wente

Extract

View articletitled, mRNA nuclear export at a glance

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OPINION

Looking beyond death: a morphogenetic role for the TNF signalling pathway

Sam J. Mathew,Dirk Haubert,Martin Krönke,Maria Leptin

Abstract

View articletitled, Looking beyond death: a morphogenetic role for the TNF signalling pathway

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COMMENTARY

Ena/VASP: towards resolving a pointed controversy at the barbed end

James E. Bear,Frank B. Gertler

Abstract

View articletitled, Ena/VASP: towards resolving a pointed controversy at the barbed end

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SPECKLE MICROSCOPY UPDATES

Shifting views on the leading role of the lamellipodium in cell migration: speckle tracking revisited

Pascal Vallotton,J. Victor Small

Extract

View articletitled, Shifting views on the leading role of the lamellipodium in cell migration: speckle tracking revisited

Supplementary information

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Testing the lamella hypothesis: the next steps on the agenda

Gaudenz Danuser

Extract

View articletitled, Testing the lamella hypothesis: the next steps on the agenda

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SHORT REPORT

Lipin is required for efficient breakdown of the nuclear envelope in Caenorhabditis elegans

Mátyás Gorjánácz,Iain W. Mattaj

Abstract

View articletitled, Lipin is required for efficient breakdown of the nuclear envelope in Caenorhabditis elegans

Supplementary information

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RESEARCH ARTICLE

Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope

Andy Golden,Jun Liu,Orna Cohen-Fix

Abstract

View articletitled, Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope

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Role of kinesin-1 and cytoplasmic dynein in endoplasmic reticulum movement in VERO cells

Marcin J. Woźniak,Becky Bola,Kim Brownhill,Yen-Ching Yang,Vesselina Levakova,Victoria J. Allan

Abstract

View articletitled, Role of kinesin-1 and cytoplasmic dynein in endoplasmic reticulum movement in VERO cells

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Radiation-induced mitotic catastrophe in PARG-deficient cells

Jean-Christophe Amé,Elise Fouquerel,Laurent R. Gauthier,Denis Biard,François D. Boussin,Françoise Dantzer,Gilbert de Murcia,Valérie Schreiber

Abstract

View articletitled, Radiation-induced mitotic catastrophe in PARG-deficient cells

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Syntaxin 3 and SNAP-25 pairing, regulated by omega-3 docosahexaenoic acid, controls the delivery of rhodopsin for the biogenesis of cilia-derived sensory organelles, the rod outer segments

Jana Mazelova,Nancy Ransom,Lisa Astuto-Gribble,Michael C. Wilson,Dusanka Deretic

Abstract

View articletitled, Syntaxin 3 and SNAP-25 pairing, regulated by omega-3 docosahexaenoic acid, controls the delivery of rhodopsin for the biogenesis of cilia-derived sensory organelles, the rod outer segments

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γ-Tubulin-containing abnormal centrioles are induced by insufficient Plk4 in human HCT116 colorectal cancer cells

Ryoko Kuriyama,Monica Bettencourt-Dias,Ingrid Hoffmann,Marc Arnold,Lisa Sandvig

Abstract

View articletitled, γ-Tubulin-containing abnormal centrioles are induced by insufficient Plk4 in human HCT116 colorectal cancer cells

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IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway

Jian-Bin Wang,Robert Sonn,Yemmsrach K. Tekletsadik,Daniel Samorodnitsky,Mahasin A. Osman

Abstract

View articletitled, IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway

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The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase

Uwe Schlomann,Jens C. Schwamborn,Myriam Müller,Reinhard Fässler,Andreas W. Püschel

Abstract

View articletitled, The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase

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Integrin α9β1 mediates enhanced cell migration through nitric oxide synthase activity regulated by Src tyrosine kinase

Shiv K. Gupta,Nicholas E. Vlahakis

Abstract

View articletitled, Integrin α9β1 mediates enhanced cell migration through nitric oxide synthase activity regulated by Src tyrosine kinase

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MER3 is required for normal meiotic crossover formation, but not for presynaptic alignment in rice

Kejian Wang,Ding Tang,Mo Wang,Jufei Lu,Hengxiu Yu,Jiafan Liu,Baoxiang Qian,Zhiyun Gong,Xin Wang,Jianmin Chen,Minghong Gu,Zhukuan Cheng

Abstract

View articletitled, MER3 is required for normal meiotic crossover formation, but not for presynaptic alignment in rice

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IP-10 induces dissociation of newly formed blood vessels

Richard J. Bodnar,Cecelia C. Yates,Margaret E. Rodgers,Xiaoping Du,Alan Wells

Abstract

View articletitled, IP-10 induces dissociation of newly formed blood vessels

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Robust heat shock induces eIF2α-phosphorylation-independent assembly of stress granules containing eIF3 and 40S ribosomal subunits in budding yeast, Saccharomyces cerevisiae

Tomáš Groušl,Pavel Ivanov,Ivana Frydlová,Pavla Vašicová,Filip Janda,Jana Vojtová,Kateřina Malínská,Ivana Malcová,Lenka Nováková,Dana Janošková,Leoš Valášek,Jiří Hašek

Abstract

View articletitled, Robust heat shock induces eIF2α-phosphorylation-independent assembly of stress granules containing eIF3 and 40S ribosomal subunits in budding yeast, Saccharomyces cerevisiae

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TORC1 controls degradation of the transcription factor Stp1, a key effector of the SPS amino-acid-sensing pathway in Saccharomyces cerevisiae

Chun-Shik Shin,Sun Young Kim,Won-Ki Huh

Abstract

View articletitled, TORC1 controls degradation of the transcription factor Stp1, a key effector of the SPS amino-acid-sensing pathway in Saccharomyces cerevisiae

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An integral protein of the inner nuclear membrane localizes to the mitotic spindle in mammalian cells

Charlotta Buch,Robert Lindberg,Ricardo Figueroa,Santhosh Gudise,Evgeny Onischenko,Einar Hallberg

Abstract

View articletitled, An integral protein of the inner nuclear membrane localizes to the mitotic spindle in mammalian cells

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EFA6A encodes two isoforms with distinct biological activities in neuronal cells

Cristina Sironi,Tambet Teesalu,Anna Muggia,Gabriele Fontana,Fortunata Marino,Sara Savaresi,Daniela Talarico

Abstract

View articletitled, EFA6A encodes two isoforms with distinct biological activities in neuronal cells

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Contractility-dependent actin dynamics in cardiomyocyte sarcomeres

Aneta Skwarek-Maruszewska,Pirta Hotulainen,Pieta K. Mattila,Pekka Lappalainen

Abstract

View articletitled, Contractility-dependent actin dynamics in cardiomyocyte sarcomeres

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Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling

Amra Hajdo-Milasinovic,Rob A. van der Kammen,Zvezdana Moneva,John G. Collard

Abstract

View articletitled, Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling

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A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation

Molly K. Nyholm,Salim Abdelilah-Seyfried,Yevgenya Grinblat

Abstract

View articletitled, A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation

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CDK2 is required for proper homologous pairing, recombination and sex-body formation during male mouse meiosis

Alberto Viera,Julio S. Rufas,Inés Martínez,José L. Barbero,Sagrario Ortega,José A. Suja

Abstract

View articletitled, CDK2 is required for proper homologous pairing, recombination and sex-body formation during male mouse meiosis

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ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT

Myosin II regulates extension, growth and patterning in the mammalian cochlear duct

Norio Yamamoto,Takayuki Okano,Xuefei Ma,Robert S. Adelstein,Matthew W. Kelley

View articletitled, Myosin II regulates extension, growth and patterning in the mammalian cochlear duct

Expression of the Arf tumor suppressor gene is controlled by Tgfβ2 during development

Natalie E. Freeman-Anderson,Yanbin Zheng,Amy C. McCalla-Martin,Louise M. Treanor,Yi D. Zhao,Phillip M. Garfin,Tong-Chuan He,Michelle N. Mary,J. Derek Thornton,Colleen Anderson,Melissa Gibbons,Raya Saab,Shannon H. Baumer,John M. Cunningham,Stephen X. Skapek

View articletitled, Expression of the Arf tumor suppressor gene is controlled by Tgfβ2 during development

IN THIS ISSUE

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Accepted manuscripts alert

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Accepted manuscripts

Centrosome amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation

Anu Prakash, Shishir Paunikar, Mark Webber, Emma McDermott, Sri H. Vellanki, Kerry Thompson, Peter Dockery, Hanne Jahns, James A. L. Brown, Ann M. Hopkins, Emer Bourke

Time-resolved proximity biotinylation implicates a porin protein in export of transmembrane malaria parasite effectors

David Anaguano, Watcharatip Dedkhad, Carrie F. Brooks, David W. Cobb, Vasant Muralidharan

Light Activated BioID (LAB): an optically activated proximity labeling system to study protein-protein interactions

Omer Shafraz, Carolyn Marie Orduno Davis, Sanjeevi Sivasankar

Transcription inhibition suppresses nuclear blebbing and rupture independent of nuclear rigidity

Isabel K. Berg, Marilena L. Currey, Sarthak Gupta, Yasmin Berrada, Bao V. Nguyen, Mai Pho, Alison E. Patteson, J. M. Schwarz, Edward J. Banigan, Andrew D. Stephens

Key role for Rac in the early transcriptional response to ECM stiffness and the stiffness-dependent repression of ATF3

Irène Dang, Joseph A. Brazzo, Yongho Bae, Richard K. Assoian

More accepted manuscripts

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Issues

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STICKY WICKET

CELL SCIENCE AT A GLANCE

OPINION

COMMENTARY

SPECKLE MICROSCOPY UPDATES

SHORT REPORT

RESEARCH ARTICLE

ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT

IN THIS ISSUE

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