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Volume 121, Issue 6

March 2008

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Cover image

Cover Image

Cover: Fibrogenic myofibroblasts grown for 24 hours on the probe cantilever (red) of an atomic force microscope develop stress fibres that stain positive for ${alpha}$ -smooth-muscle actin (green) − just as do myofibroblasts grown on standard culture surfaces. See article by P. Pittet et al. (pp. 877-886).
Table of contents

ISSN 0021-9533

EISSN 1477-9137

In this issue

COMMENTARY
SHORT REPORT
RESEARCH ARTICLE
IN THIS ISSUE
ARTICLE OF INTEREST IN OTHER COB JOURNALS
- FROM DEVELOPMENT

COMMENTARY

Cadherin switching

Margaret J. Wheelock,Yasushi Shintani,Masato Maeda,Yuri Fukumoto,Keith R. Johnson

Abstract

View articletitled, Cadherin switching

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Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

Paola Bovolenta,Pilar Esteve,Jose Maria Ruiz,Elsa Cisneros,Javier Lopez-Rios

Abstract

View articletitled, Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

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SHORT REPORT

Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis

Maithreyi Narasimha,Anne Uv,Alena Krejci,Nicholas H. Brown,Sarah J. Bray

Abstract

View articletitled, Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis

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RESEARCH ARTICLE

Signal-dependent export of GABA transporter 1 from the ER-Golgi intermediate compartment is specified by a C-terminal motif

Hesso Farhan,Veronika Reiterer,Alexander Kriz,Hans-Peter Hauri,Margit Pavelka,Harald H. Sitte,Michael Freissmuth

Abstract

View articletitled, Signal-dependent export of GABA transporter 1 from the ER-Golgi intermediate compartment is specified by a C-terminal motif

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Ca²⁺-store-dependent and -independent reversal of Stim1 localization and function

Jeremy T. Smyth,Wayne I. DeHaven,Gary S. Bird,James W. Putney, Jr

Abstract

View articletitled, Ca2+-store-dependent and -independent reversal of Stim1 localization and function

Supplementary information

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LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein

Celia J. Parkyn,Esmeralda G. M. Vermeulen,Roy C. Mootoosamy,Claire Sunyach,Christian Jacobsen,Claus Oxvig,Søren Moestrup,Qiang Liu,Guojun Bu,Angela Jen,Roger J. Morris

Abstract

View articletitled, LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein

Supplementary information

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Extracellular matrix retention of thrombospondin 1 is controlled by its conserved C-terminal region

Josephine C. Adams,Amber A. Bentley,Marc Kvansakul,Deborah Hatherley,Erhard Hohenester

Abstract

View articletitled, Extracellular matrix retention of thrombospondin 1 is controlled by its conserved C-terminal region

Supplementary information

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Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPα during axonal extension in hippocampal neurons

Katharina E. Cosker,Sadaf Shadan,Michiel van Diepen,Clive Morgan,Michelle Li,Victoria Allen-Baume,Carl Hobbs,Patrick Doherty,Shamshad Cockcroft,Britta J. Eickholt

Abstract

View articletitled, Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPα during axonal extension in hippocampal neurons

Supplementary information

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The PKCδ -Abl complex communicates ER stress to the mitochondria – an essential step in subsequent apoptosis

Xin Qi,Daria Mochly-Rosen

Abstract

View articletitled, The PKCδ -Abl complex communicates ER stress to the mitochondria – an essential step in subsequent apoptosis

Supplementary information

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Gα12 regulates protein interactions within the MDCK cell tight junction and inhibits tight-junction assembly

Ernesto Sabath,Hideyuki Negoro,Sarah Beaudry,Manuel Paniagua,Susanne Angelow,Jagesh Shah,Nicholas Grammatikakis,Alan S. L. Yu,Bradley M. Denker

Abstract

View articletitled, Gα12 regulates protein interactions within the MDCK cell tight junction and inhibits tight-junction assembly

Supplementary information

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Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption

Daniel Spazierer,Julia Raberger,Karin Groß,Peter Fuchs,Gerhard Wiche

Abstract

View articletitled, Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption

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Distinct endocytic recycling of myelin proteins promotes oligodendroglial membrane remodeling

Christine Winterstein,Jacqueline Trotter,Eva-Maria Krämer-Albers

Abstract

View articletitled, Distinct endocytic recycling of myelin proteins promotes oligodendroglial membrane remodeling

Supplementary information

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Chemical genetic analysis of the regulatory role of Cdc2p in the S. pombe septation initiation network

Sandra Dischinger,Andrea Krapp,Linfeng Xie,James R. Paulson,Viesturs Simanis

Abstract

View articletitled, Chemical genetic analysis of the regulatory role of Cdc2p in the S. pombe septation initiation network

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IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration

Lars Dan Johansen,Tiina Naumanen,Astrid Knudsen,Nina Westerlund,Irina Gromova,Melissa Junttila,Christina Nielsen,Trine Bøttzauw,Aviva Tolkovsky,Jukka Westermarck,Eleanor T. Coffey,Marja Jäättelä,Tuula Kallunki

Abstract

View articletitled, IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration

Supplementary information

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Quantitative live-cell analysis of microtubule-uncoupled cargo-protein sorting in the ER

Anna Dukhovny,Andreas Papadopulos,Koret Hirschberg

Abstract

View articletitled, Quantitative live-cell analysis of microtubule-uncoupled cargo-protein sorting in the ER

Supplementary information

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Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds

Philippe Pittet,Kyumin Lee,Andrzej J. Kulik,Jean-Jacques Meister,Boris Hinz

Abstract

View articletitled, Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds

Supplementary information

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The dynamics of fluorescently labeled endogenous gurken mRNA in Drosophila

Angela M. Jaramillo,Timothy T. Weil,Joseph Goodhouse,Elizabeth R. Gavis,Trudi Schupbach

Abstract

View articletitled, The dynamics of fluorescently labeled endogenous gurken mRNA in Drosophila

Supplementary information

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FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts

Marcin P. Iwanicki,Tomas Vomastek,Robert W. Tilghman,Karen H. Martin,Jayashree Banerjee,Philip B. Wedegaertner,J. Thomas Parsons

Abstract

View articletitled, FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts

Supplementary information

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Mechanism of PHERES1 imprinting in Arabidopsis

Grigory Makarevich,Corina B. R. Villar,Aleksandra Erilova,Claudia Köhler

Abstract

View articletitled, Mechanism of PHERES1 imprinting in Arabidopsis

Supplementary information

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L- and S-endoglin differentially modulate TGFβ1 signaling mediated by ALK1 and ALK5 in L₆E₉ myoblasts

Soraya Velasco,Patricia Alvarez-Muñoz,Miguel Pericacho,Peter ten Dijke,Carmelo Bernabéu,José M. López-Novoa,Alicia Rodríguez-Barbero

Abstract

View articletitled, L- and S-endoglin differentially modulate TGFβ1 signaling mediated by ALK1 and ALK5 in L6E9 myoblasts

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IN THIS ISSUE

ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly

Tsubasa Tanaka,Akira Nakamura

View articletitled, The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly

Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans

Christopher V. Gabel,Faustine Antonie,Chiou-Fen Chuang,Aravinthan D. T. Samuel,Chieh Chang

View articletitled, Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans

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Accepted manuscripts alert

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Accepted manuscripts

Key role for Rac in the early transcriptional response to ECM stiffness and the stiffness-dependent repression of ATF3

Irène Dang, Joseph A. Brazzo, Yongho Bae, Richard K. Assoian

Characterisation of TbSmee1 suggests endocytosis allows surface-bound cargo to enter the trypanosome flagellar pocket

Daja Schichler, Antonia Konle, Eva-Maria Spath, Sina Riegler, Alexandra Klein, Anna Seleznev, Sisco Jung, Timothy Wuppermann, Noah Wetterich, Alyssa Borges, Elisabeth Meyer-Natus, Katharina Havlicek, Sonia Pérez Cabrera, Korbinian Niedermüller, Sara Sajko, Maximilian Dohn, Xenia Malzer, Emily Riemer, Tuguldur Tumurbaatar, Kristina Djinovic-Carugo, Gang Dong, Christian J. Janzen, Brooke Morriswood

Epithelial mechanics are maintained by inhibiting cell fusion with age in Drosophila

Ari S. Dehn, Levi Duhaime, Navdeep Gogna, Patsy M. Nishina, Kristina Kelly, Vicki P. Losick

Vimentin intermediate filaments provide structural stability to the mammalian Golgi apparatus

Teresa Vitali, Rosa Sanchez-Alvarez, Tomasz M. Witkos, Ioannis Bantounas, Marie F. A. Cutiongco, Michal Dudek, Guanhua Yan, Alexander A. Mironov, Joe Swift, Martin Lowe

SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression

Parisa Naeli, Xu Zhang, Patric Harris Snell, Susanta Chatterjee, Muhammad Kamran, Reese Jalal Ladak, Nick Orr, Thomas Duchaine, Nahum Sonenberg, Seyed Mehdi Jafarnejad

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