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Volume 121, Issue 11
June 2008
Journal of Cell Science Cover Image for Volume 121, Issue 11
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  • Cover image

    Cover Image

    Issue cover image
    Cover: Drosophila spermatogenesis − sperm tails (green or yellow) coil in the base of the testes before storage in the seminal vesicles (solid yellow structures) and release into the ejaculatory duct, where accessory gland (striated structures) secretions are added. Red bars in testes are F-actin structures with roles in sperm individualisation. See article by Texada et al. (p. 1926).
  • PDF Icon PDF LinkTable of contents
ISSN 0021-9533
EISSN 1477-9137

ESSAY

The importance of stupidity in scientific research
Martin A. Schwartz
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COMMENTARY

Integrin-dependent phagocytosis – spreading from microadhesion to new concepts
Aurélien G. Dupuy,Emmanuelle Caron
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Single-cell force spectroscopy
Jonne Helenius,Carl-Philipp Heisenberg,Hermann E. Gaub,Daniel J. Muller
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RESEARCH ARTICLE

Plasma membrane recruitment of dephosphorylated β-catenin upon activation of the Wnt pathway
Jolita Hendriksen,Marnix Jansen,Carolyn M. Brown,Hella van der Velde,Marco van Ham,Niels Galjart,G. Johan Offerhaus,Francois Fagotto,Maarten Fornerod
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Myosin II regulates the shape of three-dimensional intestinal epithelial cysts
Andrei I. Ivanov,Ann M. Hopkins,G. Thomas Brown,Kirsten Gerner-Smidt,Brian A. Babbin,Charles A. Parkos,Asma Nusrat
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Zygotically controlled F-actin establishes cortical compartments to stabilize furrows during Drosophila cellularization
Anna Marie Sokac,Eric Wieschaus
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UV-induced degradation of securin is mediated by SKP1-CUL1-βTrCP E3 ubiquitin ligase
M. Cristina Limón-Mortés,Mar Mora-Santos,Águeda Espina,José A. Pintor-Toro,Antonio López-Román,María Tortolero,Francisco Romero
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Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins
Vincenzo Favaloro,Milan Spasic,Blanche Schwappach,Bernhard Dobberstein
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Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band – implications for hereditary myopathies
Atsushi Fukuzawa,Stephan Lange,Mark Holt,Anna Vihola,Virginie Carmignac,Ana Ferreiro,Bjarne Udd,Mathias Gautel
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Identification of a novel N-terminal hydrophobic sequence that targets proteins to lipid droplets
John K. Zehmer,René Bartz,Pingsheng Liu,Richard G. W. Anderson
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Mitochondrial nucleoids undergo remodeling in response to metabolic cues
Martin Kucej,Blanka Kucejova,Ramiah Subramanian,Xin Jie Chen,Ronald A. Butow
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Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis
Tohru Matsuki,Albéna Pramatarova,Brian W. Howell
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Replication-timing-correlated spatial chromatin arrangements in cancer and in primate interphase nuclei
Florian Grasser,Michaela Neusser,Heike Fiegler,Tobias Thormeyer,Marion Cremer,Nigel P. Carter,Thomas Cremer,Stefan Müller
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Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin
Yvonne Lüke,Hafida Zaim,Iakowos Karakesisoglou,Verena M. Jaeger,Lorenz Sellin,Wenshu Lu,Maria Schneider,Sascha Neumann,Asa Beijer,Martina Munck,V. C. Padmakumar,Joachim Gloy,Gerd Walz,Angelika A. Noegel
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The R246S hot-spot p53 mutant exerts dominant-negative effects in embryonic stem cells in vitro and in vivo
Ming Kei Lee,Kanaga Sabapathy
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The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle–kinesin-II dissociation in vertebrate photoreceptors
Bryan L. Krock,Brian D. Perkins
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Novel self-association of the APC molecule affects APC clusters and cell migration
Zhuoyu Li,Karin Kroboth,Ian P. Newton,Inke S. Näthke
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yuri gagarin is required for actin, tubulin and basal body functions in Drosophila spermatogenesis
Michael J. Texada,Rebecca A. Simonette,Cassidy B. Johnson,William J. Deery,Kathleen M. Beckingham
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A new model for hemoglobin ingestion and transport by the human malaria parasite Plasmodium falciparum
Michelle D. Lazarus,Timothy G. Schneider,Theodore F. Taraschi
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IN THIS ISSUE

Actin' to form furrows
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IFT proteins: not created equal
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β-catenin: to the membrane and back
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How to grow a dendrite with reelin
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Making sense of the M-band
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ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT
Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor
Grant I. Miura,Jean-Yves Roignant,Michel Wassef,Jessica E. Treisman
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The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability
Esther M. N. Dohmann,Mitchell P. Levesque,Lieven De Veylder,Ilka Reichardt,Gerd Jürgens,Markus Schmid,Claus Schwechheimer
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Accepted manuscripts
Human disease variants of KATNIP fail to support CILK1 activation and control of primary cilia
Evan H. Carpenter, Cheuk Ying Chu, Ana Limerick, David L. Brautigan, Zheng Fu
Transcriptional adaptation after deletion of Cdc42 in primary T cells
Adam M. Rochussen, Claire Y. Ma, Gillian M. Griffiths
The adhesion plaque mediates fluid discharge and duplication of the contractile vacuole complex in Trypanosoma cruzi
Ingrid Augusto, Wendell Girard Dias, Alejandra Schoijet, Guillermo Daniel Alonso, Veronica Jimenez, Wanderley de Souza, Kildare Miranda
RHOA-dependent regulation of mitochondrial remodeling and cell motility in hypoxia-exposed gastric epithelial cells
Aranya Pal, Prabin Bawali, Abhisek Brahma, Smruti Ranjan Rana, Rakesh Mohapatra, Debashish Chakraborty, Indrajit Poirah, Supriya Samal, Smaran Banerjee, Duane T. Smoot, Hassan Ashktorab, Asima Bhattacharyya
Chemically tunable FOXM1-D sensor revealed FOXM1 direct influence on cell cycle
Kriengkrai Phongkitkarun, Porncheera Chusorn, Maliwan Kamkaew, Supawan Jamnongsong, Eric W.-F. Lam, Chamras Promptmas, Somponnat Sampattavanich
More accepted manuscripts

JCS fast-track option

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Special Issue – Cell Biology of Mitochondria

Our special issue on ‘Cell Biology of Mitochondria’ is now complete. Explore this issue and read the Editorial from our Guest Editors Ana J. García-Sáez and Heidi McBride.

Save the date – Imaging Cell Dynamics

Journal of Cell Science Meeting 2026 Imaging Cell Dynamics Date: 11 – 14 May 2026 Venue: Montanyà Hotel, Catalonia, Spain. Register your interest

We are delighted to announce that we will be hosting a 2026 Imaging Cell Dynamics meeting. This meeting will provide a unique opportunity to bring together experts working at the interface between cell biology and imaging. Save the date for 11-14 May 2026 and register for more information.

Origin and evolution of mitochondrial inner membrane composition

In this Review, Kailash Venkatraman and colleagues provide an examination of the morphological similarities between prokaryotic intracytoplasmic membranes and mitochondrial inner membranes, and whether cristae evolution has driven specialisation of the mitochondrial lipidome.

Resolution in super-resolution microscopy

Super-resolution microscopy (SRM) has emerged as a powerful tool for biological discovery. In this Perspective, Kirti Prakash and colleagues compile expert opinions on crucial, yet often overlooked, aspects of SRM that are essential for maximising its benefits and advancing the field.

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