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Mechanobiology

Visit our collection pages to access primary research and review articles in your area of interest.

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RESEARCH ARTICLE
Ground-state pluripotent stem cells are characterized by Rac1-dependent cadherin-enriched F-actin complexes
Shiying Liu; Yue Meng; Xi Lan; Rong Li; Pakorn Kanchanawong
12 March 2025
https://doi.org/10.1242/jcs.263811
REVIEW
Feeling the force from within – new tools and insights into nuclear mechanotransduction
Julien Morival; Anna Hazelwood; Jan Lammerding
10 March 2025
https://doi.org/10.1242/jcs.263615
RESEARCH ARTICLE
Dynamic mechanisms for membrane skeleton transitions
Mayte Bonilla-Quintana; Andrea Ghisleni; Nils C. Gauthier; Padmini Rangamani
28 February 2025
https://doi.org/10.1242/jcs.263473
REVIEW
The emerging roles of the endoplasmic reticulum in mechanosensing and mechanotransduction
Jonathan Townson; Cinzia Progida
20 February 2025
https://doi.org/10.1242/jcs.263503
RESEARCH ARTICLE
Cadherins and growth factor receptors – ligand-selective mechano-switches at cadherin junctions
Vinh Vu; Brendan Sullivan; Evan Hebner; Zainab Rahil; Yubo Zou; Deborah Leckband
17 February 2025
https://doi.org/10.1242/jcs.262279
REVIEW
Actin from within – how nuclear myosins and actin regulate nuclear architecture and mechanics
Marta Gawor; Lilya Lehka; Danielle Lambert; Christopher P. Toseland
10 February 2025
https://doi.org/10.1242/jcs.263550
RESEARCH ARTICLE
Shear stress-stimulated AMPK couples endothelial cell mechanics, metabolism and vasodilation
Nicholas M. Cronin; Logan W. Dawson; Kris A. DeMali
18 December 2024
https://doi.org/10.1242/jcs.262232
RESEARCH ARTICLE
A microtubule stability switch alters isolated vascular smooth muscle Ca 2+ flux in response to matrix rigidity
Robert T. Johnson; Finn Wostear; Reesha Solanki; Oliver Steward; Alice Bradford; Christopher Morris; Stefan Bidula; Derek T. Warren
12 November 2024
https://doi.org/10.1242/jcs.262310
REVIEW
Cell–cell junctions in focus – imaging junctional architectures and dynamics at high resolution
Vera Janssen; Stephan Huveneers
31 October 2024
https://doi.org/10.1242/jcs.262041
REVIEW
HIV-1 assembly – when virology meets biophysics
Claire Lacouture; Baptiste Carrio; Cyril Favard; Delphine Muriaux
15 October 2024
https://doi.org/10.1242/jcs.262064
REVIEW
Principles and regulation of mechanosensing
Stefano Sala; Alexia Caillier; Patrick W. Oakes
19 September 2024
https://doi.org/10.1242/jcs.261338
RESEARCH ARTICLE | REVIEW COMMONS TRANSFER
Nucleocytoplasmic transport senses mechanical forces independently of cell density in cell monolayers
Ignasi Granero-Moya; Valeria Venturini; Guillaume Belthier; Bart Groenen; Marc Molina-Jordán; Miguel González-Martín; Xavier Trepat; Jacco van Rheenen; Ion Andreu; Pere Roca-Cusachs
09 September 2024
https://doi.org/10.1242/jcs.262363
SHORT REPORT
Controversy in mechanotransduction – the role of endothelial cell–cell junctions in fluid shear stress sensing
Shaka X; Claire Aitken; Vedanta Mehta; Blanca Tardajos-Ayllon; Jovana Serbanovic-Canic; Jiayu Zhu; Bernadette Miao; Ellie Tzima; Paul Evans; Yun Fang; Martin A. Schwartz
09 September 2024
https://doi.org/10.1242/jcs.262348
RESEARCH ARTICLE
Computational modeling establishes mechanotransduction as a potent modulator of the mammalian circadian clock
Emmet A. Francis; Padmini Rangamani
09 September 2024
https://doi.org/10.1242/jcs.261782
RESEARCH ARTICLE
SETD3 is a mechanosensitive enzyme that methylates actin on His73 to regulate mitochondrial dynamics and function
Vaibhav Deshmukh; James F. Martin
26 July 2024
https://doi.org/10.1242/jcs.261268
REVIEW
Tetraspanin proteins in membrane remodeling processes
Raviv Dharan; Raya Sorkin
25 July 2024
https://doi.org/10.1242/jcs.261532
REVIEW
Mechanical regulation of lymphocyte activation and function
Aashli Pathni; Kaustubh Wagh; Ivan Rey-Suarez; Arpita Upadhyaya
12 July 2024
https://doi.org/10.1242/jcs.219030
RESEARCH ARTICLE
DLC1 promotes mechanotransductive feedback for YAP via RhoGAP-mediated focal adhesion turnover
Aukie Hooglugt; Miesje M. van der Stoel; Apeksha Shapeti; Beau F. Neep; Annett de Haan; Hans van Oosterwyck; Reinier A. Boon; Stephan Huveneers
30 April 2024
https://doi.org/10.1242/jcs.261687
REVIEW
Positive and negative durotaxis – mechanisms and emerging concepts
Mathilde Mathieu; Aleksi Isomursu; Johanna Ivaska
22 April 2024
https://doi.org/10.1242/jcs.261919
RESEARCH ARTICLE
Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling
Jo Nguyen; Lu Wang; Wen Lei; Yechen Hu; Nitya Gulati; Carolina Chavez-Madero; Henry Ahn; Howard J. Ginsberg; Roman Krawetz; Matthias Brandt; Timo Betz; Penney M. Gilbert
27 March 2024
https://doi.org/10.1242/jcs.261666
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