Cell migration

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RESEARCH ARTICLE

Talin, a Rap1 effector for integrin activation at the plasma membrane, also promotes Rap1 activity by disrupting sequestration of Rap1 by SHANK3

Zhongji Liao; Sanford J. Shattil

26 February 2025

https://doi.org/10.1242/jcs.263595

RESEARCH ARTICLE

Cell migration signaling through the EGFR-VAV2-Rac1 pathway is sustained in endosomes

Itziar Pinilla-Macua; Sachin Surve; Alexander Sorkin

24 January 2025

https://doi.org/10.1242/jcs.263541

RESEARCH ARTICLE

Borg5 restricts contractility and motility in epithelial MDCK cells

David Cohen; Dawn Fernandez; Francisco Lázaro-Diéguez; Beatrix Überheide; Anne Müsch

10 December 2024

https://doi.org/10.1242/jcs.261705

RESEARCH ARTICLE

PTEN and the PTEN-like phosphatase CnrN have both distinct and overlapping roles in a Dictyostelium chemorepulsion pathway

Kristen M. Consalvo; Ramesh Rijal; Steven L. Beruvides; Ryan Mitchell; Karissa Beauchemin; Danni Collins; Jack Scoggin; Jerome Scott; Richard H. Gomer

01 August 2024

https://doi.org/10.1242/jcs.262054

PERSPECTIVE

Perspectives in collective cell migration – moving forward

Samantha J. Stehbens; Elena Scarpa; Melanie D. White

21 June 2024

https://doi.org/10.1242/jcs.261549

RESEARCH ARTICLE

Rear cortex contraction aids in nuclear transit during confined migration by increasing pressure in the cell posterior

Jeremy Keys; Brian C. H. Cheung; Margaret A. Elpers; Mingming Wu; Jan Lammerding

20 June 2024

https://doi.org/10.1242/jcs.260623

RESEARCH ARTICLE

Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility

Wei Wang; Paul Atherton; Maaike Kreft; Lisa te Molder; Sabine van der Poel; Liesbeth Hoekman; Patrick Celie; Robbie P. Joosten; Reinhard Fässler; Anastassis Perrakis; Arnoud Sonnenberg

16 May 2024

https://doi.org/10.1242/jcs.262116

RESEARCH ARTICLE

DLC1 promotes mechanotransductive feedback for YAP via RhoGAP-mediated focal adhesion turnover

Aukie Hooglugt; Miesje M. van der Stoel; Apeksha Shapeti; Beau F. Neep; Annett de Haan; Hans van Oosterwyck; Reinier A. Boon; Stephan Huveneers

30 April 2024

https://doi.org/10.1242/jcs.261687

RESEARCH ARTICLE

MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells

Signe Meng; Ester E. Sørensen; Muthulakshmi Ponniah; Jeppe Thorlacius-Ussing; Roxane Crouigneau; Tanja Larsen; Magnus T. Borre; Nicholas Willumsen; Mette Flinck; Stine F. Pedersen

30 April 2024

https://doi.org/10.1242/jcs.261608

REVIEW

Positive and negative durotaxis – mechanisms and emerging concepts

Mathilde Mathieu; Aleksi Isomursu; Johanna Ivaska

22 April 2024

https://doi.org/10.1242/jcs.261919

RESEARCH ARTICLE

Filopodial protrusion driven by density-dependent Ena–TOCA-1 interactions

Thomas C. A. Blake; Helen M. Fox; Vasja Urbančič; Roshan Ravishankar; Adam Wolowczyk; Edward S. Allgeyer; Julia Mason; Gaudenz Danuser; Jennifer L. Gallop

21 March 2024

https://doi.org/10.1242/jcs.261057

RESEARCH ARTICLE

Steroid hormone signaling synchronizes cell migration machinery, adhesion and polarity to direct collective movement

Mallika Bhattacharya; Michelle Starz-Gaiano

08 March 2024

https://doi.org/10.1242/jcs.261164

SHORT REPORT

Neutrophil motility is regulated by both cell intrinsic and endothelial cell ARPC1B

Ashley Peterson; David Bennin; Michael Lasarev; Julia Chini; David J. Beebe; Anna Huttenlocher

12 February 2024

https://doi.org/10.1242/jcs.261774

SHORT REPORT

RhoU forms homo-oligomers to regulate cellular responses

Natasha S. Clayton; Richard G. Hodge; Elvira Infante; Dominic Alibhai; Felix Zhou; Anne J. Ridley

30 January 2024

https://doi.org/10.1242/jcs.261645

RESEARCH ARTICLE

Stiffness-dependent MSC homing and differentiation into CAFs – implications for breast cancer invasion

Neha Saxena; Soura Chakraborty; Sarbajeet Dutta; Garvit Bhardwaj; Nupur Karnik; Omshree Shetty; Sameer Jadhav; Hamim Zafar; Shamik Sen

15 January 2024

https://doi.org/10.1242/jcs.261145

RESEARCH ARTICLE

Inactivating negative regulators of cortical branched actin enhances persistence of single cell migration

Artem I. Fokin; Arthur Boutillon; John James; Laura Courtois; Sophie Vacher; Gleb Simanov; Yanan Wang; Anna Polesskaya; Ivan Bièche; Nicolas B. David; Alexis M. Gautreau

10 January 2024

https://doi.org/10.1242/jcs.261332

PERSPECTIVE

Connecting theory and experiment in cell and tissue mechanics

Cornelia Schwayer; David B. Brückner

27 December 2023

https://doi.org/10.1242/jcs.261515

SHORT REPORT

Integrin-based adhesions promote cell–cell junction and cytoskeletal remodelling to drive embryonic wound healing

Michelle Ly; Clara Schimmer; Raymond Hawkins; Katheryn E. Rothenberg; Rodrigo Fernandez-Gonzalez

15 December 2023

https://doi.org/10.1242/jcs.261138