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Cell biology and disease

Visit our collection pages to access primary research and review articles in your area of interest.

Other subject collections

TOOLS AND RESOURCES
MitoRUSH as a tool to study the efficiency of mitochondrial import in complex I-deficient cells Available to Purchase
Michal Wasilewski; Karthik Mohanraj; Maciej Zakrzewski; Remigiusz A. Serwa; Agnieszka Chacinska
09 July 2025
https://doi.org/10.1242/jcs.263701
RESEARCH ARTICLE
Proteasome-dependent Orc6 removal from chromatin upon S-phase entry safeguards against minichromosome maintenance complex reloading and tetraploidy Available to Purchase
Yoko Hayashi-Takanaka; Ichiro Hiratani; Tokuko Haraguchi; Yasushi Hiraoka
09 July 2025
https://doi.org/10.1242/jcs.263596
PERSPECTIVE
Functional residuomics – analyzing how missense mutations impact cellular systems Available to Purchase
Guangshuo Ou
07 July 2025
https://doi.org/10.1242/jcs.263954
REVIEW
Mitochondrial topoisomerases, nucleoid architecture and mtDNA repair in human disease Available to Purchase
Sangheeta Bhattacharjee; Benu Brata Das
07 July 2025
https://doi.org/10.1242/jcs.263638
TOOLS AND RESOURCES
A single-chain antibody-based AID2 system for conditional degradation of GFP-tagged and untagged proteins Available to Purchase
Moutushi Islam; Takefumi Negishi; Naomi Kitamoto; Yuki Hatoyama; Kanae Gamo; Ken-ichiro Hayashi; Masato T. Kanemaki
04 July 2025
https://doi.org/10.1242/jcs.263961
RESEARCH ARTICLE | REVIEW COMMONS TRANSFER
A cryo-electron microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface Open Access
Lior Peer; Orly Dym; Nadav Elad; Asa Tirosh; Jossef Jacobovitch; Ehud Sivan; Mor Angel; Shira Albeck; Maya Schuldiner; Yoav Peleg; Einat Zalckvar
26 June 2025
https://doi.org/10.1242/jcs.263890
RESEARCH ARTICLE
Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting mitofusin 2 Open Access
Nikhil Dev Narendradev; Rishith Ravindran; Parul Jain; Shikha Chaudhary; Anoop Kumar G. Velikkakath; Abyasree Sudharman; Adithya Janardhanan; Tapas Chandra Nag; Subhash Chandra Yadav; Srinivasa Murty Srinivasula
20 June 2025
https://doi.org/10.1242/jcs.263830
RESEARCH ARTICLE
A data-driven model for mitochondrial inner membrane remodeling as a driving force of organelle shaping Open Access
Noga Preminger; Ben Zucker; Sarah Hassdenteufel; Till Stephan; Stefan Jakobs; Michael M. Kozlov; Maya Schuldiner
20 June 2025
https://doi.org/10.1242/jcs.263850
RESEARCH ARTICLE
Glutamine modulates stress granule formation in cancer cells through core RNA-binding proteins Open Access
Gabriel P. Faber; Gilad Gross; Oz Mualem; Matan Y. Avivi; Hiba Waldman Ben-Asher; Orly Yaron; Noa Kinor; Orit Shefi; Rakefet Ben-Yishay; Dana Ishay-Ronen; Yaron Shav-Tal
06 June 2025
https://doi.org/10.1242/jcs.263679
RESEARCH ARTICLE
The phosphorylation of Pak1 by Erk1/2 to drive cell migration requires Arl4D acting as a scaffolding protein Open Access
Ting-Wei Chang; Ming-Chieh Lin; Chia-Jung Yu; Fang-Jen S. Lee
22 May 2025
https://doi.org/10.1242/jcs.263812
RESEARCH ARTICLE
The P4-phospholipid flippase Atp11a is required for maintenance of eye and ear structure in zebrafish Open Access
Alexia Hawkey-Noble; Cameron Tobin; Muhammad T. Ameen; Liam Osmond; Colby Gill; Christina S. Bottaro; Terry-Lynn Young; Curtis R. French
22 May 2025
https://doi.org/10.1242/jcs.263657
RESEARCH ARTICLE
Coilin and SUMOylation influence PARP1 dynamics and the DNA damage response Open Access
Sara K. Tucker; Blaise C. Seale; David T. Brown; Michael D. Hebert
21 May 2025
https://doi.org/10.1242/jcs.263953
RESEARCH ARTICLE
Tumor acidosis supports cancer cell lipid uptake via a rapid transporter-independent mechanism Available to Purchase
Marc Severin; Rikke K. Hansen; Michala G. Rolver; Tove Hels; Kenji Maeda; Luis A. Pardo; Stine F. Pedersen
15 May 2025
https://doi.org/10.1242/jcs.263688
RESEARCH ARTICLE
Pyruvate plus uridine augments mitochondrial respiration and prevents cardiac hypertrophy in zebrafish and H9c2 cells Available to Purchase
Soumyajit Mukherjee; Shreya Das; Surajit Das; Samudra Gupta; Subhra Prakash Hui; Arunima Sengupta; Alok Ghosh
14 May 2025
https://doi.org/10.1242/jcs.263653
CELL SCIENCE AT A GLANCE
Quality control of un-imported mitochondrial proteins at a glance Available to Purchase
Megan Balzarini; John Kim; Hilla Weidberg
12 May 2025
https://doi.org/10.1242/jcs.263757
SHORT REPORT
Integrated proteome and lipidome analyses place OCIAD1 at the mitochondria–peroxisome intersection balancing lipid metabolism Available to Purchase
Vanessa Linke; Mateusz Chodkowski; Kacper Kaszuba; Mariusz Radkiewicz; Tina A. Schrader; Hirak Das; Vikas Rana; Dorota Stadnik; Michał Dadlez; Bettina Warscheid; Michael Schrader; Agnieszka Chacinska
09 May 2025
https://doi.org/10.1242/jcs.263729
CELL SCIENTISTS TO WATCH
An interview with Guest Editor Heidi McBride Free
08 May 2025
https://doi.org/10.1242/jcs.264070
PERSPECTIVE
A lipid in transit – the journey of cholesterol into the heart of mitochondrial research Available to Purchase
Thomas Simmen; Luca Pellegrini
08 May 2025
https://doi.org/10.1242/jcs.263907
RESEARCH ARTICLE
Definition of the human mitochondrial TOM interactome reveals TRABD as a new interacting protein Available to Purchase
Metin Özdemir; Silke Oeljeklaus; Alexander Schendzielorz; Marcel Morgenstern; Anusha Valpadashi; Roya Yousefi; Bettina Warscheid; Sven Dennerlein
24 April 2025
https://doi.org/10.1242/jcs.263576
TOOLS AND RESOURCES
A dual-purification system to isolate mitochondrial subpopulations Open Access
Corey N. Cunningham; Jonathan G. Van Vranken; Jakeline Larios; Katarina Heyden; Steven P. Gygi; Jared Rutter
14 April 2025
https://doi.org/10.1242/jcs.263693
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