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Proteostasis

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RESEARCH ARTICLE
Distinct TORC1 signalling branches regulate Adc17 proteasome assembly chaperone expression
Thomas D. Williams; Ifeoluwapo Joshua; Flavie Soubigou; Sylwia M. Dublanska; Rebecka Bergquist; Adrien Rousseau
22 July 2024
https://doi.org/10.1242/jcs.261892
RESEARCH ARTICLE
Toxicity of the model protein 3×GFP arises from degradation overload, not from aggregate formation
Shotaro Namba; Hisao Moriya
12 June 2024
https://doi.org/10.1242/jcs.261977
RESEARCH ARTICLE
The Drosophila Nesprin-1 homolog MSP300 is required for muscle autophagy and proteostasis
Kevin van der Graaf; Saurabh Srivastav; Rajkishor Nishad; Michael Stern; James A. McNew
10 June 2024
https://doi.org/10.1242/jcs.262096
RESEARCH ARTICLE
Tbl1 promotes Wnt–β-catenin signaling-induced degradation of the Tcf7l1 protein in mouse embryonic stem cells
Yang Yu; Liwei Liu; Jianjian Cao; Ru Huang; Quanchao Duan; Shou-Dong Ye
16 May 2024
https://doi.org/10.1242/jcs.261241
CELL SCIENCE AT A GLANCE
Mammalian pexophagy at a glance
Justyna Bajdzienko; Anja Bremm
16 May 2024
https://doi.org/10.1242/jcs.259775
RESEARCH ARTICLE
Collapse of late endosomal pH elicits a rapid Rab7 response via the V-ATPase and RILP
Ryan J. Mulligan; Magdalena M. Magaj; Laura Digilio; Stefanie Redemann; Chan Choo Yap; Bettina Winckler
13 May 2024
https://doi.org/10.1242/jcs.261765
RESEARCH ARTICLE
Multi-monoubiquitylation controls VASP-mediated actin dynamics
Laura E. McCormick; Cristian Suarez; Laura E. Herring; Kevin S. Cannon; David R. Kovar; Nicholas G. Brown; Stephanie L. Gupton
26 January 2024
https://doi.org/10.1242/jcs.261527
RESEARCH ARTICLE
A ubiquitin–proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis
Toan Khanh Le; Yasuhiro Hirano; Haruhiko Asakawa; Koji Okamoto; Tatsuo Fukagawa; Tokuko Haraguchi; Yasushi Hiraoka
03 October 2023
https://doi.org/10.1242/jcs.260930
RESEARCH ARTICLE
Surf4 collaborates with derlin-2 and derlin-1 to mediate cyclooxygenase-2 translocation to the cytosol for degradation
Shu-Fen Chen; Chun-Hu Wu; Yen-Ming Lee; Kabik Tam; Jun-Yang Liou; Song-Kun Shyue
28 September 2023
https://doi.org/10.1242/jcs.260995
RESEARCH ARTICLE
The E3 ubiquitin ligase CHIP drives monoubiquitylation-mediated nuclear import of the tumor suppressor PTEN
Shrabastee Chakraborty; Subhajit Karmakar; Malini Basu; Satadeepa Kal; Mrinal K. Ghosh
22 September 2023
https://doi.org/10.1242/jcs.260950
CELL SCIENCE AT A GLANCE
Chloroplast protein translocation pathways and ubiquitin-dependent regulation at a glance
Sreedhar Nellaepalli; Anne Sophie Lau; R. Paul Jarvis
21 September 2023
https://doi.org/10.1242/jcs.241125
RESEARCH ARTICLE
Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion
Nathaniel L. Hepowit; Bradley Moon; Adam C. Ebert; Robert C. Dickson; Jason A. MacGurn
25 July 2023
https://doi.org/10.1242/jcs.260675
RESEARCH ARTICLE
EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration
Dan Li; Suat Peng Neo; Jayantha Gunaratne; Kanaga Sabapathy
16 June 2023
https://doi.org/10.1242/jcs.260427
CELL SCIENCE AT A GLANCE
Aggrephagy at a glance
Bernd Bauer; Sascha Martens; Luca Ferrari
31 May 2023
https://doi.org/10.1242/jcs.260888
RESEARCH ARTICLE
The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function
William R. Critchley; Gina A. Smith; Ian C. Zachary; Michael A. Harrison; Sreenivasan Ponnambalam
25 May 2023
https://doi.org/10.1242/jcs.260657
RESEARCH ARTICLE
Coupled protein quality control during nonsense-mediated mRNA decay
Alison J. Inglis; Alina Guna; Ángel Gálvez-Merchán; Akshaye Pal; Theodore K. Esantsi; Heather R. Keys; Evgeni M. Frenkel; Robert Oania; Jonathan S. Weissman; Rebecca M. Voorhees
23 May 2023
https://doi.org/10.1242/jcs.261216
RESEARCH ARTICLE
Septins and K63 ubiquitin chains are present in separate bacterial microdomains during autophagy of entrapped Shigella
Damián Lobato-Márquez; José Javier Conesa; Ana Teresa López-Jiménez; Michael E. Divine; Jonathan N. Pruneda; Serge Mostowy
13 April 2023
https://doi.org/10.1242/jcs.261139
REVIEW
Ubiquitin and its relatives as wizards of the endolysosomal system
Ilana Berlin; Aysegul Sapmaz; Virginie Stévenin; Jacques Neefjes
24 February 2023
https://doi.org/10.1242/jcs.260101
RESEARCH ARTICLE
Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling
Vaishna Vamadevan; Neelam Chaudhary; Subbareddy Maddika
15 December 2022
https://doi.org/10.1242/jcs.260284
RESEARCH ARTICLE
Arih2 regulates Hedgehog signaling through smoothened ubiquitylation and ER-associated degradation
Bo Lv; Xiao-Ou Zhang; Gregory J. Pazour
22 August 2022
https://doi.org/10.1242/jcs.260299
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