New developments in microscopy and electrophysiology have brought a renewal of interest in methods of micromanipulation.

A number of features desirable in the design of a micromanipulator is discussed.

A new micromanipulator is described. Its outstanding features are (1) single control; (2) massive construction with freedom from vibration; (3) freedom from play; (4) continuous variability of sensitivity; (5) limitation of range of movement to the field of view; (6) rapid low-power centring; (7) unusual robustness combined with delicacy of movement achieved without any high-precision methods. The performance of the instrument is adequate for high-power cytological work and for microdissection by phase-contrast illumination.

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