A freezing-thawing method for rupturing mast cells has made it possible to show that each of the secretory granules is surrounded by a regular network of filaments forming a basket-like structure. The filaments attach to the membrane with hook-like structures. Immunoelectron microscopy of intact mast cells shows that actin occurs mainly in the subplasmalemmal space, whereas in ruptured cells it is seen around granules, indicating that the granule network might consist of actin.
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JOURNAL ARTICLE| 01 May 1990
A filamentous network surrounding secretory granules from mast cells
Department of Anatomy and Cytology, Odense University, Denmark.
Online Issn: 1477-9137
Print Issn: 0021-9533
© 1990 by Company of Biologists
J Cell Sci (1990) 96 (1): 43–46.
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E.H. Nielsen; A filamentous network surrounding secretory granules from mast cells. J Cell Sci 1 May 1990; 96 (1): 43–46. doi: https://doi.org/10.1242/jcs.96.1.43
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