Nuclear division in Schizosaccharomyces pombe has been studied in transmission electron micrographs of sections of cells fixed by a method of freeze-substitution. We have found cytoplasmic microtubules in the vicinity of the spindle pole bodies and two kinds of microtubules, short discontinuous ones and long, parallel ones in the intranuclear mitotic spindle. For most of the time taken by nuclear division the spindle pole bodies face each other squarely across the nuclear space but early in mitosis they briefly appear twisted out of alignment with each other, thereby imparting a sigmoidal shape to the bundle of spindle microtubules extending between them. This configuration is interpreted as indicating active participation of the spindle in the initial elongation of the dividing nucleus. It is proposed that mitosis is accompanied by the shortening of chromosomal microtubules simultaneously with the elongation of the central pole-to-pole bundle of microtubules of the intranuclear spindle. Daughter nuclei are separated by the sliding apart of interdigitating microtubules of the spindle at telophase. Some of the latter bear dense knobs at their ends.
2020 JCS Prize winner: Tadayoshi Murakawa
Congratulations to Tadayoshi Murakawa, who won the 2020 JCS Prize for his paper entitled ‘An autophagy-dependent tubular lysosomal network synchronizes degradative activity required for muscle remodeling’. Find out more about Tadayoshi and read his winning paper.
'FocalPlane features...' webinar series
We’re excited to announce the new 'FocalPlane features…' webinar series. Covering all aspects of microscopy, join us on the first Tuesday of every month to hear about the latest research and take part in a virtual networking session with the speaker afterwards.
Save your spot at our next sessions:
6 July
Speaker: Eva Nogales
3 August
Speaker: Michael Dustin
Meet the JCS Editors
Cell scientist to watch - Liang Ge
Now in his fourth year of running his own lab, Liang Ge tells us about his journey to becoming a PI at Tsinghua University, discusses autophagy and UPS, and shares the best piece of science-related advice he’s received.
Read & Publish agreement with EIFL
We are pleased to announce that researchers in 30 developing and transition economy countries can benefit from immediate and fee-free Open Access publishing in Journal of Cell Science following a new agreement with Electronic Information for Libraries (EIFL).
We now have over 200 institutions in more than 20 countries and six library consortia participating in our read & Publish initiative. Find out more and view the full list of participating institutions.
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